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Clinical Trial Summary

A clinical characterization of a large cohort of patients with different severities of AD and ocular symptoms/atopic keratoconjunktivitis (AKC). The data will contribute to assess the frequency of complications in order to give a rationale for focused prevention and treatment strategy.


Clinical Trial Description

Atopic Dermatitis (AD), a very common inflammatory skin condition of child and adulthood, is strongly associated with ocular disease. Accordingly, about 20% experience conjunctivitis at some point, and many have chronic disease. Atopic keratoconjunctivitis (AKC) is the most feared as it may lead to blindness. Little is known about the etiology, the immune infiltrate, as well as predictive factors of AKC and the clinical characteristics of AD patients who develop this entity. We expect this project to enable clinicians to better identify AKC patients in the future as well as improve the understanding of the pathogenesis of AKC. The ocular findings will be compared between AD severity and a control group without ocular symptoms. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04973384
Study type Observational
Source Rigshospitalet, Denmark
Contact Pernille Rævdal, MD
Phone +4520804435
Email pernille.raevdal.01@regionh.dk
Status Recruiting
Phase
Start date August 5, 2021
Completion date June 2024

See also
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Completed NCT03379311 - A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and Perennial Allergic Conjunctivitis Phase 1
Recruiting NCT04296864 - Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC) Phase 2
Completed NCT00987467 - Long-term Topical Cyclosporine for Atopic Keratoconjunctivitis N/A