Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation

Athletic Performance Clinical Trial

Official title:

Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04320446
• Other study ID #: Nº 507/CEIH/2018
• Status: Completed
• Phase: N/A
• Start date: June 1, 2019
• Est. completion date: November 30, 2019

Study information

• Verified date: March 2020
• Source: Universidad de Granada
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Maximal fat oxidation during exercise (MFO) and the intensity of exercise that elicits MFO (Fatmax) has been recognized as potential determinants of endurance performance.

The purpose of this study was to determine the possible interaction between the effects of diurnal variation (morning vs. afternoon) and caffeine ingestion on MFO, Fatmax and VO2 max in endurance-trained men. Specifically, the investigators sought to elucidate whether the stimulant actions of caffeine could reverse the decrements of MFO and Fatmax observed in the morning.

Description:

Body weight, height, body composition (DXA), exercise test (MFO and VO2max assessment) will be measured during the 4 evaluations.

Participants were randomized into 4 exercise test conditions:

1. Exercise test in the morning with placebo intake

2. Exercise test in the evening with placebo intake

3. Exercise test in the morning with caffeine intake

4. Execrise test in the evening with caffeine intake

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Est. completion date: November 30, 2019
• Est. primary completion date: November 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Having a body mass index (BMI) ranged from 18.5 to 28 kg/m2

• not suffering any specific disease which can be aggravated by physical exercise

• having previous experience in endurance training (i.e. self-reporting at least 2 years of cycling or running training including more than 3 training sessions/week).

• Participant must be capable and willing to provide consent, understand exclusion criteria, instructions and protocols.

Exclusion Criteria:

• Being smoker

• Taking medication or drugs

• Any non-controlled medical condition which could influence results or could be worsened by the participation in the study

• Are deemed unsuitable by the investigator for any other reason, that prevent data collection.

Related Conditions & MeSH terms

• Athletic Performance
• Energy Metabolism

Intervention

Behavioral:
• Test in the morning
The exercise test was performed between 8 a.m and 11 a.m
• Test in the afternoon
The exercise test was performed between 5 p.m. and 8 p.m.a

Locations

Country	Name	City	State
Spain	Instituto Mixto Universitario Deporte Salud	Granada

Sponsors (1)

Lead Sponsor	Collaborator
Universidad de Granada

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MFO	Maximal fat oxidation during exercise	Through study completion, an average of 1 month
Secondary	FATmax	The intensity of exercise that elicits MFO	Through study completion, an average of 1 month
Secondary	VO2max	Cardiorrespiratory fitness measured by maximal oxygen uptake	Through study completion, an average of 1 month