Athletic Performance Clinical Trial
Official title:
Effects of Alpha-glycerylphosphorylcholine on Physical and Cognitive Performances in Varsity Volleyball Players
In order to attain the elite level on the national scene, volleyball players need several
attributes. In addition to mastering technical and tactical skills, great jumping ability is
another important asset. Maximal power output needed to achieve height during a jump
necessitates coordinated neuromuscular recruitment and muscle mass among others.
Interestingly, there are claims that alpha-glycerylphosphorylcholine (A-GPC) increases
acetylcholine synthesis and enhances exercise-induced increases in plasma growth hormone
concentrations, two factors that could theoretically be associated neuromuscular
transmission and muscle mass.
However, until now only a few studies have investigated the role of A-GPC in human exercise
performance. Published results were mixed. One recent study showed that isometric peak force
was slightly but significantly increased when subjects had ingested a daily dose of 600 mg
of A-GPC over a period of 6 days (Bellar et al., JISSN, 2015).
The objective of our study is to evaluate the longer-term effects (4 weeks) using a higher
dose (1000 mg/day) of A-GPC on jumping capabilities in elite male and female volleyball
players.
Our study design will be a placebo controlled, randomized, double-blind, crossover study. Varsity male and female volleyball players (n=28) will each be asked to participate in both arms of the study, i.e. placebo and A-GPC (1000 mg/kg/day). The duration of each arm of the study will be 4 weeks separated by a 7-day washout period. The order of treatment (placebo or A-GPC) will be determined randomly. Athletes will be asked to maintain their training load during the duration of the experiment. ;
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