To Explore the Effects of Different Training Periods and Dietary Pattern on the Gut Microbiota, Metabolites and Protein Expression Levels of Strength and Endurance Athletes and to Find Relevant Biological Indicators.

Athlete Clinical Trial

Official title:

Sports Science Institute

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04710667
• Other study ID #: IRB-19-039-B1
• Status: Recruiting
• Start date: October 30, 2020
• Est. completion date: February 3, 2021

Study information

• Verified date: January 2021
• Source: National Taiwan Sport University
• Contact: YuChih Lin
• Phone: +886961546309
• Email: jarling217015[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The gastrointestinal tract contains hundreds of millions of microorganisms, collectively called the intestinal flora, which plays an important role in the health of the host. Many studies have also confirmed that the composition and function of the intestinal flora can be changed through the training chain. Changes in the composition of intestinal microbes can affect exercise performance, energy metabolism, oxidative stress, immune function, inflammation, and tissue repair. Therefore, maintaining a healthy gut microbial balance is essential for athletes' health, training, nutritional status, and athletic performance. This project intends to use metagenomics, proteomics, and metabolomics and other technologies to systematically explore the effects of different training periods and dietary interventions on the intestinal flora of muscle strength and endurance athletes. , Protein expression and the influence of metabolites. In the plan, explore the differences in the intestinal flora between muscle strength and endurance sports athletes during the preparation period, competition period, and transition period, and collect blood and feces to perform protein and metabolite molecular changes. It is hoped that through the smooth implementation of this research project, the research results can be applied to personalized diet planning, improve intestinal adaptability and the effectiveness of sports nutrition intervention, and then adjust athletes' status and improve sports performance to win the highest honor for the country in the arena.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 24
• Est. completion date: February 3, 2021
• Est. primary completion date: February 3, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 30 Years

Eligibility

Inclusion Criteria:

• 20-30 years old healthy muscle strength and endurance sports athletes

Exclusion Criteria:

1. Exclude cardiovascular disease, hypertension, metabolic disease, asthma, or neuromuscular sports injuries within six months, etc.

2. Exclude those who regularly take lactic acid bacteria-related foods for a long time

3. Exclude students and related stakeholders under the guidance of the project host

Related Conditions & MeSH terms

• Athlete

Locations

Country	Name	City	State
Taiwan	National Taiwan Sport University	Taoyuan City

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan Sport University

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Differences in intestinal flora of athletes in sports during preparation, competition and transition periods	asparate aminotransferase?alanine aminotransferase?albumin?blood urea nitrogen Creatinine?uric acid?total cholesterol?triacylglycerol?High-density lipoprotein?Low density lipoprotein?Free fatty acid?glucose?creatine kinase?gut microbiota	2021/1/1-2021/2/28