Clinical Trials Logo

Clinical Trial Summary

A placebo-controlled, factorial trial to assess the impact of rosuvastatin and tranexamic acid (TXA) in patients undergoing noncardiac surgery who are at risk of a perioperative cardiovascular event.


Clinical Trial Description

The POISE-3 pilot is a randomized controlled trial of 100 patients with, or at risk of, atherosclerotic disease who are undergoing noncardiac surgery. Utilizing a partial factorial design, the POISE-3 pilot will determine the effect of rosuvastatin versus placebo and TXA versus placebo in the perioperative setting. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02546648
Study type Interventional
Source McMaster University
Contact
Status Completed
Phase Phase 3
Start date February 2015
Completion date August 2016

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT03314818 - Natural History of Carotid Plaque as Determined by 3D Ultrasound N/A
Recruiting NCT03480568 - Alirocumab in Patients on a Stable Dialysis Regimen Phase 3
Recruiting NCT02176941 - Telomeres and Arterial Aging N/A
Completed NCT00673985 - Edwards Lifesciences Self-Expanding Stent Peripheral Vascular Disease Study N/A
Completed NCT00090168 - Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED) Phase 3
Completed NCT00738725 - BioImage Study: A Clinical Study of Burden of Atherosclerotic Disease in an At-Risk Population N/A
Completed NCT00352222 - Safety and Efficacy of Express LD to Treat Stenosed or Occlusive Atherosclerotic Disease in Iliac Arteries Phase 3
Completed NCT02462005 - Treatment of Femoro-popliteal Atherosclerotic Lesions Using the Ranger Paclitaxel Coated Balloon Catheter. All Comers Registry.