Effects of Different Inhalation Oxygen Concentrations on Postoperative

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

This study was a single-center, prospective, randomized controlled, two-arm study. This study will be conducted in the First Hospital of China Medical University. the investigators aimed to investigate the effects of different inspired oxygen concentrations in lung protective ventilation strategies on immediate postoperative atelectasis and intraoperative changes of oxygenation index in patients undergoing neurosurgical surgery in the supine position. A total of 96 neurosurgical patients under supine position were selected with an estimated operation time of more than 2 hours. Patients were randomly assigned to low-oxygen concentration (30%FiO2) L group, or high-oxygen concentration (60%FiO2) H group, and both groups received lung protective ventilation strategies. The main outcome was the comparison of postoperative atelectasis volume between the two groups. Secondary outcomes were the comparison of intraoperative oxygenation index and postoperative changes in diaphragm height between the two groups. ;

Study Design

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Clinical Trial Details

NCT number	NCT05627024
Study type	Interventional
Source	China Medical University, China
Contact	Wenfei Tan
Phone	+862483283100
Email	winfieldtan@hotmail.com
Status	Recruiting
Phase	Phase 4
Start date	January 11, 2023
Completion date	June 1, 2024

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Effects of Different Inhalation Oxygen Concentrations on Postoperative Atelectasis — DIOCA

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms