Evaluation of Effect of Different Ventilator Mods on Atelectasis in Patients Undergoing Laparoscopic Surgery

Atelectasis Clinical Trial

— PCV-VG  

Official title:

Evaluation of Effect of Different Ventilator Mods on Atelectasis in Patients Undergoing Laparoscopic Surgery: a Prospective Randomized Controlled Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03614845
• Other study ID #: DerinceTRH-006
• Status: Completed
• Phase: N/A
• Start date: September 1, 2018
• Est. completion date: September 15, 2019

Study information

• Verified date: November 2019
• Source: Derince Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this study researchers aim to evaluate effect of different ventilation modalities on the developments of atelectasis by using ultrasound.

Description:

Patients undergoing laparoscopic surgery will be randomly assigned either volume controlled ventilation group or pressure controlled volume guaranteed ventilation group. All patients will be performed lung ultrasonography pre and postoperatively to evaluate the development of lung atelectasis and effect of different ventilation modalities on the development of atelectasis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 62
• Est. completion date: September 15, 2019
• Est. primary completion date: September 15, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• undergoing laparoscopic surgery

• ASA Status I-II

Exclusion Criteria:

• Gastroesophageal reflux

• obstructive sleep apnea syndrome

• BMI>30

• severe lung and heart disease

• ASA Status III-IV

Related Conditions & MeSH terms

• Atelectases, Postoperative Pulmonary
• Atelectasis
• Pulmonary Atelectasis

Intervention

Procedure:
• VCV
after induction for anesthesia patients will be supported by mechanical ventilation on volume controlled ventilation mode
• PCV-VG
after induction for anesthesia patients will be supported by mechanical ventilation on pressure controlled and volume guaranteed ventilation mode

Diagnostic Test:
• lung ultrasonography
all patients will be performed lung ultrasonography pre and postoperatively

Locations

Country	Name	City	State
Turkey	Marmara University School of Medicine	Istanbul
Turkey	Derince Research and Training Hospital	Kocaeli

Sponsors (1)

Lead Sponsor	Collaborator
Derince Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Effect of different ventilation mods on development of peroperative atelectasis	Patients undergoing laparoscopic surgery will be assigned either volume controlled mode or pressure support volume guaranteed mode. After the operation a researcher will perform lung ultrasonography postoperative at minute 5. Researcher will detect 6 region of each lung totally 12 regions . The researcher will record the modified and original lung ultrasonography scores (LUS Score) of the patients. LUS Score is a scoring system to evaluate atelectasis of lung and scores 1-3 points for each region (Min score 0 max score 36)	at minute 5 in postoperative care unit
Secondary	Effect of different ventilation mods on development of peroperative atelectasis	Patients undergoing laparoscopic surgery will be assigned either volume controlled mode or pressure support volume guaranteed mode. After the operation a researcher will perform lung ultrasonography in postoperative care unit at minute 30. Researcher will detect 6 region of each lung totally 12 regions . The researcher will record the modified and original lung ultrasonography scores (LUS Score) of the patients. LUS Score is a scoring system to evaluate atelectasis of lung and scores 1-3 points for each region.(Min score 0 max score 36)	at minute 30 in postoperative care unit