Atelectasis Clinical Trial
Official title:
Role of Lung Ultrasound Imaging for Intraoperative Monitoring of Atelectasis During Laparoscopic Surgery
General anesthesia results in the development of atelectasis in the dependent areas of the
lungs exposing patients to an increased risk of hypoxemia. During laparoscopic procedures,
pneumoperitoneum increases already present atelectasis.
Several methods have been suggested to reduce the impact of atelectasis during surgery.
However, few intraoperative modalities for the diagnosis and monitoring of atelectasis are
available. Lung ultrasound imaging is a promising non-invasive, non-radiant, portable and
easy to use tool that as yet to be studied in the intraoperative setting.
This observational study will aim to clarify the role of lung ultrasound imaging during
laparoscopic surgery for the diagnostic and monitoring of atelectasis.
This study is designed to:
- Demonstrate a link between the lung ultrasound aeration score, the partial pressure of
oxygen in arterial blood (PaO2) / fraction of inspired oxygen (FiO2) ratio and the
oxygenation index.
- In the event of intraoperative desaturation, study the impact of positive
end-expiratory pressure (PEEP) and/or increase of FiO2 on the aeration score.
- Study the impact of pain on diaphragmatic function and the aeration score.
Our hypothesis is that lung ultrasound imaging allows detection of lung aeration changes
associated with induction of general anesthesia, pneumoperitoneum, emergence from anesthesia
and changes occurring during the stay in the recovery room.
On arrival in the operating theatre, each patient will undergo a baseline lung ultrasound
examination.
The anesthetic technique and monitoring will be standardized. The radial artery will be
cannulated after induction of anesthesia for blood gas monitoring.
Lung ultrasound examinations will be performed 5 minutes following induction of general
anesthesia and 5 minutes after insufflation of the abdomen with carbon dioxide. In the event
of a desaturation needing an intervention (increase of FiO2 or PEEP), ultrasound imaging
will be repeated before and after the intervention. Presence of a pneumothorax or
endobronchial intubation will be assessed during each examination. Fifteen minutes after
arrival and immediately before discharge from the recovery room, lung ultrasound
examinations will also be performed.
FiO2 and vital signs will be recorded at each ultrasound examination. Arterial blood samples
will be collected simultaneously. Pain rating using the visual analog scale and
diaphragmatic function will be assessed during the preoperative ultrasound examination and
before discharge from the recovery room.
;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06021249 -
Comparing Innovative and Traditional Ventilation Strategies on Atelectasis and Prognosis in Elderly Patients
|
N/A | |
| Terminated |
NCT03581474 -
Evaluation of BAL Procedure With Ambu aScope 3 Large in Patients in an ICU Setting
|
N/A | |
| Completed |
NCT02871258 -
MetaNeb® Chest X-ray Study
|
N/A | |
| Completed |
NCT02523755 -
Evaluation of Regional Distribution of Ventilation During Labor With or Without Epidural Analgesia
|
Phase 4 | |
| Completed |
NCT02232841 -
Electrical Impedance Imaging of Patients on Mechanical Ventilation
|
N/A | |
| Completed |
NCT02216006 -
High Fresh Gas Flow After Intubation
|
N/A | |
| Completed |
NCT01416519 -
Physiotherapy Technique Decreases Respiratory Complications After Cardiac Operation
|
N/A | |
| Completed |
NCT03153592 -
Effects of Mechanical Ventilation Guided by Transpulmonary Pressure on Gas Exchange During Robotic Surgery: a Pilot Study
|
N/A | |
| Completed |
NCT03694665 -
Monitoring Lung Recruitment Maneuver in Anesthetized Morbidly Obese
|
N/A | |
| Completed |
NCT04506203 -
The Accuracy of Pediatric Air Test as a Non-invasive Atelectasis Diagnostic Tool
|
N/A | |
| Not yet recruiting |
NCT06296173 -
Open Lung Protective Extubation Following General Anesthesia
|
N/A | |
| Completed |
NCT04006665 -
Role of Lung Ultrasonography in Diagnosing Atelectasis in Robotic Pelvic Surgeries
|
||
| Completed |
NCT03614845 -
Evaluation of Effect of Different Ventilator Mods on Atelectasis in Patients Undergoing Laparoscopic Surgery
|
N/A | |
| Active, not recruiting |
NCT06075836 -
AI Assisted Detection of Chest X-Rays
|
||
| Completed |
NCT01993394 -
Effect of Hyperoxia and Hypergravity on Lung Ventilation and Perfusion
|
N/A | |
| Completed |
NCT00671723 -
Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis Patients
|
N/A | |
| Completed |
NCT03378752 -
Atelectasis Formation Using HFJV During Stereotactic Solid Organ Ablations
|
||
| Completed |
NCT05963945 -
Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice
|
||
| Completed |
NCT03592589 -
Prevention of Atelectasis, Via High Flow Nasal Cannula to Obtain a PEP, During General Anesthesia in Children
|
N/A | |
| Completed |
NCT04458623 -
Air Test In Diagnosis Of Postoperative Lung Atelectasis
|
N/A |