Aetiology of Asymmetrical Hearing Loss: A Retro-spective Study Thesis Submitted for Partial Fulfillment of Master Degree in Audio-Vestibular Medicine

Asymmetrical Hearing Loss Clinical Trial

Official title:

Aetiology of Asymmetrical Hearing Loss: A Retro-spective Study Thesis Submitted for Partial Fulfillment of Master Degree in Audio-Vestibular Medicine

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05543135
• Other study ID #: Soh-Med-22-07-09
• Status: Not yet recruiting
• Start date: September 20, 2022
• Est. completion date: September 2023

Study information

• Verified date: September 2022
• Source: Sohag University
• Contact: Enas M Mahrous, resident doctor
• Phone: 01096769904
• Email: inas_mahmoud_post[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Hearing loss maybe: -Symmetrical: in which the severity and pattern of hearing loss are the same in each ear. Or -Asymmetrical: is defined as binaural difference in bone conduction thresholds of >10 dB at two consecutive frequencies or >20 dB at one frequency (0.25-8.0 kHz), Poorer speech perception will often accompany poorer hearing and may be the reason for the patient's presentation .Unilateral or asymmetrical sensorineural hearing loss is important to discern, as it is an important risk factor for auditory nerve tumors (i.e. vestibular schwannoma) which is a life threatening condition, and in such cases further investigation is required (i.e. MRI scan) unless there is a known reason for the asymmetry, Several reports have recommended that further evaluation, especially expensive imaging studies, be conducted to rule out acoustic tumors when AHL is present

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: September 2023
• Est. primary completion date: September 2023
• Gender: All
• Age group: 6 Years and older

Eligibility

Inclusion Criteria:

• Age: 6 years old and more.
• Sex: male and female.

Exclusion Criteria:

• Age: less than 6 years old.
• Patients with symmetrical hearing loss.

Related Conditions & MeSH terms

• Asymmetrical Hearing Loss
• Deafness
• Hearing Loss

Intervention

Diagnostic Test:
• basic audiological evaluation
pure tone audiometry&immitancemetry

Locations

Country	Name	City	State
Egypt	Sohag University Hospital	Sohag

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Dunn CC, Tyler RS, Oakley S, Gantz BJ, Noble W. Comparison of speech recognition and localization performance in bilateral and unilateral cochlear implant users matched on duration of deafness and age at implantation. Ear Hear. 2008 Jun;29(3):352-9. doi: 10.1097/AUD.0b013e318167b870. — View Citation

Margolis RH, Saly GL. Asymmetric hearing loss: definition, validation, and prevalence. Otol Neurotol. 2008 Jun;29(4):422-31. doi: 10.1097/MAO.0b013e31816c7c09. — View Citation

Peng AW, Salles FT, Pan B, Ricci AJ. Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction. Nat Commun. 2011 Nov 1;2:523. doi: 10.1038/ncomms1533. Review. — View Citation

Plack CJ, Barker D, Hall DA. Pitch coding and pitch processing in the human brain. Hear Res. 2014 Jan;307:53-64. doi: 10.1016/j.heares.2013.07.020. Epub 2013 Aug 11. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Asymmetrical hearing loss	asymmetrical hearing loss using basic audiological evalution &imaging	1 year