Clinical Trials Logo
  1. Home
  2. Asthma in Children
  3. NCT03099902
  4. Details
NCT03099902 Clinical Trial

Secondhand Smoking in Asthmatic Children

Asthma in Children Clinical Trial

Official title:
Association Between Maternal Smoking and GSTP1 and TNFa Polymorphism in Children With Asthma/Wheezing

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03099902
Other study ID # 14/1-3-2011
Secondary ID
Status Completed
Phase N/A
First received March 22, 2017
Last updated April 10, 2017
Start date November 1, 2010
Est. completion date September 1, 2015

Study information
Verified date April 2017
Source AHEPA University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study will investigate the interaction between GSTP1 / TNFa polymorphisms and passive smoking in children with asthma/wheezing. Contemporary second hand-smoke exposure will be confirmed by laboratory testing.

Recruitment information / eligibility
Status Completed
Enrollment 90
Est. completion date September 1, 2015
Est. primary completion date September 1, 2015
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 12 Months to 18 Years
Eligibility Inclusion Criteria:

- Subjects 1-18 years old with doctor diagnosed asthma/wheezing

Exclusion Criteria:

- Premature birth (< 36 gestation weeks)

- Asthma-like symptoms due to other conditions (infectious, congenital, mechanical)

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Lung function
Spirometry test
• White blood cell DNA extraction
GSTP1 and TNFa polymorphisms with PCR
• Urinary testing
Urinary nicotine and cotinine detection

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
AHEPA University Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary GSTP1 and TNFa variants in children with asthma 0 days
See also
  Status Clinical Trial Phase
Completed NCT04450108 - Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients N/A
Recruiting NCT05734261 - Forced Oscillations Technique During a Metacholine Test in Children N/A
Recruiting NCT06044051 - Dynamics of the Upper and Lower Airway Respiratory Microbiomes Associated With Severe Infant Asthma N/A
Completed NCT04896502 - Effectiveness of Telemedicine Home Assessments for Identification and Reduction of Asthma Triggers N/A
Completed NCT03503812 - Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches N/A
Not yet recruiting NCT05902702 - Isotonic Saline for Children With Bronchiolitis N/A
Not yet recruiting NCT05547477 - Continuous EMG Measurements in Children With Asthma During Sleep
Completed NCT04388098 - Oral Health Status of Asthmatic Children
Terminated NCT03586544 - Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity Phase 4
Recruiting NCT04821908 - Consequences of COVID 19 Pandemic on Childhood Asthma
Not yet recruiting NCT03277170 - Pragmatic RCT of High-dose Oral Montelukast for Moderate and Severe Pediatric Acute Asthma Exacerbations Phase 2
Enrolling by invitation NCT06239844 - Navigating Together for Equitable Asthma Management for Children in Families Who Communicate in Language Other Than English N/A
Recruiting NCT06003569 - Reducing Asthma Attacks in Disadvantaged School Children With Asthma N/A
Not yet recruiting NCT05974917 - Serious gaMes as Emerging E-health Interventions for Young People With neurologicaL or rEspiratory disoRders
Not yet recruiting NCT05997784 - Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing
Recruiting NCT05366309 - Performance and Adherence in Children Using Spacers N/A
Completed NCT05684926 - COVID-19 Pandemic Asthma Child Telerehabilitation Yoga N/A
Recruiting NCT04166344 - A mHealth Intervention to Improve Symptom Control in Children and Adolescents With Difficult-to-control Asthma N/A
Completed NCT03673618 - Soluble Corn Fiber Supplementation for Asthma Phase 2
Completed NCT05576142 - Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma