Asthma, Bronchial Clinical Trial
Official title:
The Cohort Study for Asthma in China: an Prospective Observational Study
The study is to establish a standardized asthma cohort study, build an information network platform system and a biospecimen bank for asthma cohort, establish clear follow-up standards and norms, observe the asthma outcomes and identify biomarkers to predict asthma outcomes.
This is a single center observational prospective longitudinal cohort study to establish a standardized asthma cohort, consisting of 400 patients with asthma. Baseline data including lung function test, chest CT, induced sputum, etc. was collected and the patients were followed up for 2 or more years. Subjects who met the 2023 GINA diagnostic criteria for asthma and were able to participate in the study according to the protocol and sign the informed consent were included. No additional investigational drugs will be applied to the patients. Blood samples are transported to designated laboratories for safekeeping and biomarker testing. We aimed to explore the mechanism of biomarkers involved in asthma pathogenesis and identify treatable traits related to disease outcome. Full analysis set will be used for all analyses. Missing data will be analyzed as it is. Statistical analysis will be conducted by epidemiology & statistics work group from Chinese Academy of Sciences, using SAS and SUDAAN software. An electronic data capture system will be used in this study. Paper-based questionnaire administration will also be used. Questionnaire variables will be checked before data entry. During the study, PI will be in charge of the monitoring of the whole procedure. Working group will do the data cleaning and data analyzing. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00734318 -
Study of FlutiForm® Versus Fluticasone Plus Formoterol in Adult Subjects With Severe Asthma
|
Phase 3 | |
| Completed |
NCT00825903 -
The Effects of Exercise on Physiological and Psychological Parameters in an Asthmatic Population
|
N/A | |
| Terminated |
NCT00385593 -
Symbicort Single Inhaler Therapy vs Conventional Best Practice for the Treatment of Persistent Asthma in Adults
|
Phase 3 | |
| Completed |
NCT00213252 -
Use of Montelukast to Treat Children With Mild to Moderate Acute Asthma
|
Phase 2 | |
| Completed |
NCT00092092 -
Study of Montelukast and Its Effect on Lower Leg Growth in Children With Asthma (MK-0476-254)
|
Phase 4 | |
| Completed |
NCT00489346 -
A Study to Evaluate MK0476 and Fluticasone to Control Asthma in Patients With Mild Persistent Asthma (0476-910)
|
Phase 3 | |
| Withdrawn |
NCT03989635 -
Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma.
|
Phase 2 | |
| Withdrawn |
NCT00540839 -
A Study of Montelukast (MK-0476) Compared With Fluticasone in Pediatric Participants With Chronic Asthma (MK-0476-303)
|
Phase 3 | |
| Recruiting |
NCT06299306 -
REACT - REAl Care for AsThma - A Disease Study to Identify Patients With Severe Uncontrolled Asthma
|
||
| Recruiting |
NCT00312312 -
Allergy Towards Grass and Bronchial Inflammation - Related to Immunotherapy and Exhaled Nitrogen Oxide
|
N/A | |
| Completed |
NCT00092885 -
An Approved Drug to Study a New Indication for Seasonal Allergic Rhinitis in Patients With Asthma (0476-269)
|
Phase 3 | |
| Not yet recruiting |
NCT06422078 -
A Non-interventional, Prospective Study With Benralizumab
|
||
| Completed |
NCT02805907 -
Efficacy of Calcifediol Supplementation in Asthma Control in Asthmatic Patients With Vitamin D Deficiency (ACViD)
|
Phase 4 | |
| Not yet recruiting |
NCT00644462 -
Wheeze Detection in Adults During Dynamic Bronchial Situations Measured by PulmoTrack® 2010 With WIM-PC™ Technologies Recording
|
N/A | |
| Completed |
NCT03839433 -
The Mannitol-Asthma-Ciclesonide-Study
|
Phase 4 | |
| Completed |
NCT00640120 -
Wheeze Detection in Children During Dynamic Bronchial Situations Measured by WIM-PC™ Recording
|
N/A | |
| Completed |
NCT03034447 -
Sleep Apnea in Asthmatic Children and Teenagers
|
N/A | |
| Completed |
NCT05270278 -
Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy
|
||
| Withdrawn |
NCT00830427 -
A Study To Examine The Safety And Efficacy Of PF-00610355 In Moderately Asthmatic Subjects
|
Phase 2 | |
| Completed |
NCT00092105 -
Study of MK0476 (Montelukast Sodium) and Effects on Asthma and Nasal Symptoms Upon Exposure to Cats (0476-256)
|
Phase 3 |