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Asthenia clinical trials

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NCT ID: NCT06420999 Not yet recruiting - Clinical trials for Diaphragm Dysfunction

Incidence and Impact of ICU-acquired Diaphragm Weakness

PRODIGY
Start date: June 1, 2024
Phase:
Study type: Observational

ICU survivors are at an increased risk of hospital and ICU readmission. Among the complications of ICU stay, diaphragmatic dysfunction is common, with a prevalence of 60 to 80%, and is associated with increased mortality and prolonged hospital stays. Furthermore, several studies have reported that the observation of impaired respiratory muscle function upon ICU discharge is associated with a poor long-term prognosis. However, the incidence and prognostic impact of persistent diaphragmatic dysfunction at ICU discharge have never been evaluated. The measurement of dyspnea, a composite evaluation of respiratory muscle function, has not been assessed for predicting prognosis upon ICU discharge. The hypothesis of the project is that the presence of ICU-acquired diaphragmatic dysfunction at ICU discharge is associated with a poorer prognosis within 90 days.

NCT ID: NCT06409611 Not yet recruiting - Clinical trials for Intensive Care Unit Acquired Weakness

MUSCLE EFFECTS OF NEUROMUSCULAR ELECTROSTIMULATION IN MECHANICALLY VENTILATED PATIENTS IN AN ICU

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

To prevent the development of ICUAW, both early mobilization and neuromuscular electrical stimulation (NMES) have been shown to prevent muscle atrophy in critically ill patients by preserving muscle mass. Furthermore, it is of great value that muscle assessment using kinesiological ultrasound becomes routine to monitor this patient's profile with regard to strength, muscle quality and muscle mass. Our objective is to evaluate the muscular changes promoted by NMES in patients under mechanical ventilation. This is a randomized clinical trial study, which will perform NMES sessions for at least 10 days in mechanically ventilated patients. They will also undergo ultrasound assessments of the quadriceps. Patients will be divided into a control group and an NMES group. In addition, general information recorded in the medical record will be collected, such as basic characteristics, laboratory tests and general assessments.

NCT ID: NCT06407076 Not yet recruiting - Healthcare Clinical Trials

Strengths and Weaknesses of Physiotherapy in the Daily Work of an Intensive Care Unit

Start date: May 9, 2024
Phase:
Study type: Observational

Background. A stay in the Intensive Care Unit can cause long-term problems and physiological changes at the neuromuscular and respiratory levels in critically ill patients. Early physiotherapy in these patients is safe and feasible to avoid or reduce the adverse musculoskeletal and respiratory effects of the stay in this hospital unit. Objective. To identify the strengths and barriers of Physiotherapy in an Intensive Care Unit, according to the vision of different Health Science professionals. Method. Qualitative observational study using individual interviews and focus groups. 18 people (6 doctors, 6 nurses and 6 physiotherapists) will be included in the study. The 18 health professionals will participate in personal interviews and focus groups (3 focus groups with 6 participants each). Participants will be recruited from the Intensive Care Unit of the Hospital Universitario Central de Asturias. Data will be analysed using the thematic analysis approach according to Braun and Clarke's method. We will use face-to-face interviews and focus groups to collect data and analyse them through thematic analysis. Purposive sampling will be used to recruit our participants. We will continue to recruit participants, if necessary, until saturation of data from the thematic analysis is reached. Expected outcomes. To assess the knowledge, perceptions and expectations of the healthcare staff in the Intensive Care Unit regarding Physiotherapy in the management of patients admitted to this Unit. To identify the strengths of Physiotherapy in the management of these patients.

NCT ID: NCT05689697 Not yet recruiting - Patient Activation Clinical Trials

Induced Physiological Ketosis in Asthenia and\or Decreased Tolerance to Physical and\or Mental Exertion

Start date: January 9, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is evaluating of efficacy of innovative dietary strategy -stimulation of physiological ketosis with Liquid Technology Formula PanTrek, in patients with asthenia and or decreased tolerance to physical and\or mental exertion. PanTrek is a liquid formula of potassium and magnesium salts of beta-oxibutiric acid, ginsenosides and rosmarinic acid.