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Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents

Mechanical Ventilation Complication Clinical Trial

Official title:
Effects of Three Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents: a Randomized Controlled Trial

Clinical Trial Summary

The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.

Clinical Trial Description

In the study, ET cuff pressure control will be provided with pilot balloon fingers (Control Group), intermittent with a manometer (Study Group 1) and continuously with a smart cuff manager (Study Group 2). To assess the effect of different ETT cuff pressure control on microaspiration of the stomach contents, the pepsin level will be measured during deep tracheal secretions. The samples will be examined in the first four hours after intubation, all secretions collected up to the 24th hour of intubation after first sample intake and all secretions collected between 24-48 hours after intubation. Pepsin level will be considered as positive for cut-off point. In addition, the effect of different ETT cuff pressures control on the incidence of VAP will be examined. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04061083
Study type Interventional
Source Afyonkarahisar Health Sciences University
Contact
Status Completed
Phase N/A
Start date May 16, 2019
Completion date December 1, 2019
View Details
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