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Ascites clinical trials

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NCT ID: NCT02779608 Recruiting - Stomach Neoplasms Clinical Trials

The Study of Intraperitoneal Docetaxel Plus S-1 for Malignant Ascites

Start date: January 20, 2017
Phase: Phase 2
Study type: Interventional

This is a clinical Study to evaluate the effect, survival benefit and safety of intraperitoneal docetaxel combined with oral S-1 for advanced gastric cancer with malignant ascites.

NCT ID: NCT02755701 Recruiting - Cirrhosis Clinical Trials

The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites

Start date: July 2016
Phase: Phase 4
Study type: Interventional

To compare the efficacy of branched-chain amino acid in serum albumin level in cirrhotic patients with ascites.

NCT ID: NCT02724683 Recruiting - Malignant Ascites Clinical Trials

Symptomatic Ascites Drainage With a Patient-controlled Vascular Catheter.

Start date: January 2016
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to determine whether drainage with the usage of a fine, patient-controlled vascular catheter inserted into abdominal cavity is a feasible, safe and effective method in the management of symptomatic malignant ascites. Complications' rate of the procedure and patients' quality of life, nutritional status and experience on the treatment are main endpoints.

NCT ID: NCT02530398 Recruiting - Malignant Ascites Clinical Trials

A Tolerance Trial of Cinobufacini Injection Intraperitoneal Perfusion on Digestive System Cancer With Ascites

Start date: July 2015
Phase: Phase 1
Study type: Interventional

To evaluate the tolerance and safety of cinobufacini injection intraperitoneal treatment on digestive system cancer patients with malignant ascites, and propose dosage regimens for future clinical trials. The clinical trial is divided into two parts, including single and successive administration.

NCT ID: NCT02120196 Recruiting - Liver Cirrhosis Clinical Trials

Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

SBP
Start date: January 2014
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare the effectiveness of rifaximin versus norfloxacin for secondary prevention of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites.

NCT ID: NCT02022150 Recruiting - Liver Cirrhosis Clinical Trials

Body Composition Analysis in Cirrhotic Undergoing Paracentesis

Paracentesis
Start date: December 2012
Phase:
Study type: Observational

Ascites is a frequent complication of liver cirrhosis, initial treatment consists on diuretics intake, however, as the disease progresses this complication becomes more severe, consequently other therapeutic options are used. Paracentesis is indicated when severe ascites is present and it should be accompanied by albumin infusion. Nutritional status is generally affected in patients with liver cirrhosis, even more patients with severe ascites show decreased energy intake due to gastric compression.

NCT ID: NCT01852409 Recruiting - Clinical trials for Refractory Malignant Ascites

Phase I Trial of Intraperitoneal Bevacizumab in Refractory Malignant Ascites

Start date: May 2013
Phase: Phase 1
Study type: Interventional

Malignant ascites often has a profound impact on the quality of life of cancer patients. Current treatments,including dietary, medical, and procedural are often temporary and unsatisfactory options in patients approaching the end of life. Intraperitoneal bevacizumab for the palliation of malignant ascites might be a novel choice for refractory malignant ascites.

NCT ID: NCT01838538 Recruiting - Clinical trials for Ovarian Cancer With Malignant Ascites

Clinical Study in Treatment of Malignant Ascites of Ovarian Cancer With Intraperitoneal Injection Bevacizumab Combined With Intraperitoneal Hyperthermic Perfusion Chemotherapy

Start date: June 2011
Phase: Phase 2
Study type: Interventional

To study the efficacy and safety of intraperitoneal injection bevacizumab combined with intraperitoneal hyperthermic perfusion chemotherapy in treatment of malignant ascites of ovarian cancer. To analyze the clinical significance of the concentration change of vascular endothelial growth factor (VEGF) in ascites in treatment of intraperitoneal injection bevacizumab

NCT ID: NCT01558895 Recruiting - Liver Cirrhosis Clinical Trials

Infrared Ray Heat Treatment in Liver Cirrhosis Patients With Refractory Ascites

Start date: March 2012
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this study is to evaluate the therapeutic efficacy of Infrared ray heat treatment in hepatic area in cirrhosis patients with refractory ascites. The evaluation of the efficacy includes the ascites pressure, portal vein velocity,SAAG before and after the treatment. Clinical symptoms were also observed simultaneously.

NCT ID: NCT01421550 Recruiting - Liver Cirrhosis Clinical Trials

Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver Cirrhosis

CRUCIAL
Start date: January 2011
Phase: Phase 3
Study type: Interventional

The purpose of the present study is to investigate whether or not to perform elective surgical repair of umbilical hernias in patients with liver cirrhosis and ascites. There are no other randomized controlled trials in this area. The optimal management in patients with umbilical hernias and liver cirrhosis with ascites is not clear yet. The general surgical opinion is that umbilical hernias in patients with ascites should not be corrected because of the supposedly high operative risks and high recurrence rates. Conservative treatment, however, can have severe complications resulting in emergency repair. Such operations carry a higher risk of complications than elective operations, particularly in this group of patients. Prospective and retrospective series showed us that elective hernia repair in this specific patient group is safe without major complications or high recurrence rates. The aim of this study is to asses the optimal timing of correction of umbilical hernia in patients with liver cirrhosis and ascites.