Adenocarcinoma of Hepatic Flexure (Diagnosis) Clinical Trial
Official title:
A Prospective Randomized Controlled Clinical Study of Laparoscopic Right Hemicolectomy Using the Caudal-to-cranial Approach
To investigate the clinical application value of laparoscopic radical right hemicolectomy using the caudal-to-cranial approach versus the medial-to-lateral approach by prospective randomized controlled clinical study.
To compare the caudal-to-cranial approach with the medial-to-lateral approach in
laparoscopic right hemicolectomy for the advance right colon cancer.
A prospective randomized controlled trial will be performed in the GI department,the
Guangdong provincial hospital of Chinese Medicine from October 2016 to October 2024.The
sample size，150 cases with advanced right colon cancer, will be needed after calculated by
the statistics .The 150 cases will be randomly divided into two groups: laparoscopic radical
right hemicolectomy using the caudal-to-cranial(CtC) approach(GroupCtC) and laparoscopic
radical right hemicolectomy using the medial-to-lateral(MtL) approach (GroupMtL). Primary
outcomes are the operative time，The secondary outcomes are the total blood loss,the number
of lymph nodes dissected,the average time of ground activities,the time to first flatus,the
hospital stay,the intra-operative complication and the post-operative complication，and
others' outcomes are the Disease-free survival rate(DFS) at 3 years and 5 years,the Overall
survival rate（OS）at 3 years and 5 years.The data in two groups will be compared.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment