Asbestosis Clinical Trial
Official title:
OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early Diagnosis
Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and inertial properties. We believe that this technique may contribute to the early diagnosis of asbestosis.
The aims of this study were (1) to use the FOT to analyze how respiratory mechanics is
affected in patients with asbestos exposed, (2) to identify the best FOT parameters for the
diagnosis of respiratory changes in these patients (3) Assess whether the presence of
obstructive changes is associated with the smoking habit.The control group (CG) included 24
subjects with normal spirometric data and without a history of smoking or pulmonary disease
formed by workers and students UERJ and FioCruz. Volunteers with asbestos exposure were from
the Department of CESTEH/ FioCruz, totaling 24 exposed and 7 with diagnoses of asbestosis.
The diagnosis of asbestosis was established based on a history of substantial exposure to
asbestos dusts and compatible radiological features, together with exclusion of other
competing diagnoses.
The tests included a standardized questionnaire on respiratory symptoms, clinical
evaluation; Plain radiography of the chest; FOT, plethysmography and spirometry, in that
order.
;
Time Perspective: Cross-Sectional
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04161014 -
The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial
|
Phase 2 | |
Recruiting |
NCT02748798 -
Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders
|
Early Phase 1 | |
Completed |
NCT00005280 -
Specialized Center of Research in Occupational and Immunologic Lung Disease
|
N/A | |
Enrolling by invitation |
NCT04016181 -
The Edinburgh Lung Fibrosis Molecular Endotyping (ELFMEN) Study
|
||
Not yet recruiting |
NCT05133453 -
Pirfenidone Use in Asbestosis Patients: Efficacy and Prognosis
|
N/A |