Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT05269095
Other study ID # 35236/1/22
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date March 21, 2022
Est. completion date March 21, 2023

Study information

Verified date March 2022
Source Tanta University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of posterior knee (IPACK) block compared to genicular nerves block in patients undergoing knee arthroscopy.


Description:

Maintaining patient safety, ensuring best patient outcomes, and optimal pain relief post-operatively are of utmost concern for anesthesia providers. Adequate pain relief attenuates stress responses and long-term chronic pain complications while contributing to improved postoperative outcomes. Knee arthroscopy is a very common procedure and very often is performed as day-case surgery. Ambulatory arthroscopic surgery of the knee is preferred by the majority of properly selected and well-informed patients. It has been reported that a significant number of patients have moderate to severe pain 24 hours after ambulatory surgery in general and knee arthroscopy in particular and pain affects the patient's activity level and satisfaction. Adductor canal block (ACB) is a popular peripheral nerve block that has been shown to decrease the pain significantly and decrease opioid consumption with minimal effect on quadriceps function. It provides analgesia to the peri-articular and intra-articular aspects of the knee joint but doesn't relieve posterior knee pain which is moderate to severe in intensity.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 105
Est. completion date March 21, 2023
Est. primary completion date March 20, 2023
Accepts healthy volunteers No
Gender All
Age group 21 Years to 60 Years
Eligibility Inclusion Criteria: - Age 21-60 years - Both genders - American Society of Anaesthesiologists physical status classification I - III - Patients scheduled for elective unilateral knee arthroscopy under spinal anesthesia Exclusion Criteria: - Patient refusal - Preoperative neurological deficits - Opioid-dependent (opioid intake more than 3 months) - Chronic pain conditions - Significant cardiac and respiratory disease - Pre-existing major organ dysfunction such as hepatic and renal failure - Coexisting hematological disorder or deranged coagulation parameters - Psychiatric illnesses - Allergy to any of the drugs used in the study

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Spinal anesthesia only
Patients will receive spinal anesthesia with 2-3 ml 0.5% (10-15 mg) hyperbaric bupivacaine plus 25 ug fentanyl at the L3/4 interspaces.
Biological:
Spinal anesthesia and ultrasound-guided Genicular nerves block
Patients will receive16 ml bupivacaine 0025% will be administered, and4 ml of this solution will be placed at each of the 4 target nerves.
Ultrasound-guided Adductor Canal block (ACB) technique with infiltration of the interspace between popliteal artery and the capsule of posterior knee block ('PACK)
Adductor Canal block (ACB) technique will be performed using 16 ml bupivacaine 0025% As regarding the Popliteal artery and the capsule of posterior knee block ('PACK), it will be performed Using 16 ml bupivacaine 0.25%

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Tanta University

Outcome

Type Measure Description Time frame Safety issue
Primary Postoperative 24-hour rescue analgesic consumption Total postoperative 24-hour rescue analgesic consumption will be recorded 24 hours postoperative
Secondary Post-operative pain Post-operative pain will be assessed by the Numeric Rating Scale (NRS) rest and mobilization. 24 hours Postoperative
Secondary Time taken till 1st rescue analgesic request The time till administration of first rescue analgesia will be recorded 24 hours Postoperative
See also
  Status Clinical Trial Phase
Recruiting NCT06014203 - Examination of Edema After Arthroscopic Shoulder Surgery
Not yet recruiting NCT05995795 - Arthroscopic Release Of Shoulder Internal Rotation Contracture In Brachial Plexus Palsy
Not yet recruiting NCT03688529 - Analyzing the Noxious Autonomic Response During Shoulder Arthroscope Surgery
Terminated NCT00209560 - A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedures Phase 3
Recruiting NCT03699046 - Evaluating the Effectiveness of Subchondroplasty for Treating Bone Marrow Lesions of the Knee N/A
Completed NCT00492609 - Medical and Economical Evaluation of Computer-assisted Reconstruction of the Anterior Cruciate Ligament (ACL) N/A
Completed NCT02184702 - Effects of Shoulder Edema on Intubated Tube in Patients Undergoing Shoulder Arthroscopy N/A
Recruiting NCT04855877 - Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Surgery Reduce Postoperative Haemarthrosis Phase 4
Completed NCT03427775 - Multimodal Analgesia After Shoulder Arthroscopy
Enrolling by invitation NCT01052233 - Development of Knee Osteoarthritis After Arthroscopic Partial Resection of Degenerative Meniscus Tear Phase 4
Completed NCT01169389 - Analgesic Control Following Knee Arthroscopy N/A
Completed NCT00633438 - Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery Phase 4
Recruiting NCT04461431 - Clinical Study of Posterolateral Structure of Knee Joint Under Arthroscopy N/A
Not yet recruiting NCT03327337 - Arthroscopic Assisted Balloon Tibioplasty for the Treatment of Schatzker II-IV Tibial Plateau Fractures N/A
Completed NCT00633386 - Effect of Celecoxib Versus Placebo Before and After Knee Surgery on the Overall Use of Analgesics After Surgery Phase 4
Not yet recruiting NCT05222334 - Ultrasound-Guided Extrafascial Versus Intrafascial Interscalene Brachial Plexus Block in Shoulder Arthroscopy N/A
Completed NCT05165836 - Dexmedetomidine as Adjuvant in Erector Spinae Plane Block After Shoulder Arthroscopy N/A
Recruiting NCT06208774 - Pericapsular Nerve Group Block vs Interscalene Block for Shoulder Arthroscopy N/A
Recruiting NCT05646654 - Interscalene Block Versus Erector Spinae Plane Block for Shoulder Arthroscopy Anesthesia N/A
Active, not recruiting NCT04178538 - The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults N/A