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Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty

Arthroplasty Complications Clinical Trial

Official title:
Study of the Noninferiority of an Oral vs Intravenous Administration of Tranexamic Acid in Total Hip Arthroplasty

Clinical Trial Summary

To find noninferiority relationship between oral and intravenous administration of tranexamic acid on peroperative and postoperative blood loss and serum concentration during primary total hip arthroplasty.

Clinical Trial Description

Tranexamic acid is an anti-fibrinolytic drug, recommended in total hip arthroplasty to reduce peroperative and postoperative hemorrhagic complications. The original character of our study lies in the serum dosage of tranexamic acid, allowing to correlate the primary objective (blood loss) with this one. The investigators will focus on the reduction of the risks associated with the administration of intravenous medicines, the economic aspect and the ease of use. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04691362
Study type Interventional
Source University of Liege
Contact
Status Completed
Phase Phase 4
Start date January 1, 2021
Completion date December 14, 2022
View Details
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