Clinical Trials Logo

Clinical Trial Summary

The rate of hip, knee arthroplasties and their revision are increasing every year. The incidence of blood transfusion in these operations are reported 18%, 68%, and 39%, 67%, respectively. Blood transfusion is known to increase the risk of pulmonary, septic, wound and thromboembolic complications and is related to mortality. Restrictive transfusion protocols has cost-effective results in terms of reducing these complications, promoting early discharge and reduced frequency of re-admission.

Within this context, we aimed to evaluate the transfusion practice in our hospital, define the transfusion indicators and compare the transfused and non transfused patients in terms of recovery.


Clinical Trial Description

After obtaining ethical approval Patients undergoing hip or knee arthroplasty or revision arthroplasty will be included in this prospective observational study.

Patient characteristics (age , gender, body mass index, ASA physical status, anticoagulant medication) Preoperative: hemoglobin, hematocrit, platelet, INR, APTT, PT values, the precence of preoperative anemia, anemia treatment modalities will be recorded.

Intraopreative: type and duration of surgery, anesthesia method, monitoring methods used, the amount of intraoprative adminestred fluids (crystalloid-colloid), amount of hemorrhage Postoperative: hemoglobin-hematocrit-platelet leve The amount of blood transfusion and the product used (erythrocyte suspension, fresh frozen plasma, thrombocyte-fibrinogen-factor concentration-cryoprecipitate-other ) Hemoglobin-hematocrit-platelet level before and after transfusion Indications for transfusion; hemoglobin threshold / physiological transfusion indicator; tachycardia, hypotension, low flow rate, desaturation, low SvO2, inotropic requirement, etc. / comorbidities / monitorisation findings, other, Discharge time of patients Early upright position (postoperative 2nd day), information on walking capacities (TUG - The Time Up and Go test) will be recorded and compared between transfused and non-transfused patients ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03282201
Study type Observational
Source Diskapi Teaching and Research Hospital
Contact
Status Completed
Phase
Start date October 15, 2017
Completion date June 20, 2018

See also
  Status Clinical Trial Phase
Terminated NCT03940651 - Cardiac and Renal Biomarkers in Arthroplasty Surgery Phase 4
Completed NCT05593341 - Opioid Education in Total Knee Arthroplasty N/A
Not yet recruiting NCT05290818 - Total Versus Robotic Assisted Unicompartmental Knee Replacement N/A
Withdrawn NCT04099355 - Investigating the Effect of Dronabinol on Post-surgical Pain Early Phase 1
Recruiting NCT04924205 - A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy N/A
Completed NCT05399043 - Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitation N/A
Terminated NCT03185117 - Opioid Consumption After Hospital Discharge in Orthopedic Surgery
Completed NCT04118023 - 7T MRI to Evaluate Cartilage Defects in the Knee
Terminated NCT03260699 - Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA) N/A
Recruiting NCT03283878 - Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial Phase 4
Completed NCT03133481 - Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty Phase 3
Active, not recruiting NCT04684160 - Comparison of Joint Awareness Between Fixed-bearing and Mobile-bearing Total Knee Arthroplasty Using Titanium-nitride Coated Posterior-stabilized Prostheses N/A
Recruiting NCT06259032 - Comparative Effect of Mechanical and Functional Alignment in Bilateral Total Knee Arthroplasty on Ankle Alignment N/A
Completed NCT02928562 - The Impaction of Exercise Training on Bone Mineral Density in Patients After Total Knee Arthroplasty N/A
Completed NCT04481711 - Total Knee Arthroplasty and Clinical Findings N/A
Recruiting NCT01135160 - Evaluation of Weight Bearing After Total Hip and Knee Replacement
Completed NCT03921034 - IPACK Nerve Block for Total Knee Arthroplasty Phase 4
Active, not recruiting NCT05248815 - Muscle Strength and Total Knee Replacement
Not yet recruiting NCT06024161 - Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties
Not yet recruiting NCT06415825 - Preliminary Muscle Contraction in the Rehabilitation and Prevention of Degenerative Pain in the Locomotor System N/A