Arthritis, Psoriatic Clinical Trial
Official title:
Phase 2, Randomized, Parallel-group, Double-blind, Placebo-controlled Study of Sonelokimab in Patients With Active Psoriatic Arthritis
This is a study to demonstrate the clinical efficacy and safety of the nanobody® sonelokimab administered subcutaneously (sc) compared with placebo in the treatment of adult participants with active psoriatic arthritis. The study includes adalimumab treatment as an active reference arm.
Patients will be randomized to receive one of three sonelokimab treatment regimes, adalimumab or placebo. Primary efficacy evaluation will take place at Week 12. Patients will be allocated to a further 12 weeks of treatment with sonelokimab or adalimumab based on response assessment at week 12. In certain countries, treatment will end at week 12. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02181673 -
A Study of Golimumab in Participants With Active Psoriatic Arthritis
|
Phase 3 | |
| Recruiting |
NCT04936308 -
Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent
|
Phase 3 | |
| Terminated |
NCT00090129 -
Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis
|
Phase 3 | |
| Withdrawn |
NCT03625089 -
Impact of Nurse-led Programme With Carotid Ultrasound on Addressing Cardiovascular Risk in Patients With Arthritis
|
N/A | |
| Recruiting |
NCT05571696 -
Mind Matters: A High Touch, Low Cost Approach to Improving Mental Health Outcomes in Patients With Psoriatic Diseases
|
N/A | |
| Active, not recruiting |
NCT05071664 -
A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis
|
Phase 2 | |
| Completed |
NCT00938015 -
Study Evaluating Safety and Adherence to Treatment With Etanercept in Adults With Psoriatic Arthritis
|
N/A | |
| Suspended |
NCT03703934 -
Central Pain Mechanisms in Patients With Hand-Osteoarthritis, Psoriatic Arthritis and Healthy Controls
|
||
| Recruiting |
NCT05092269 -
A Long-term Extension Study of Ustekinumab in Pediatric Participants
|
Phase 3 | |
| Terminated |
NCT05083078 -
A Study of Guselkumab and Risankizumab in Healthy Participants and Participants With Psoriatic Arthritis
|
Phase 1 | |
| Completed |
NCT02436785 -
Do Inflammatory Arthritis Inpatients Receiving Group Music Therapy Improve Pain Compared to Music Listening?
|
N/A | |
| Completed |
NCT02294227 -
16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Psoriatic Arthritis
|
Phase 3 | |
| Completed |
NCT00998829 -
Study Evaluating The Prevalence Of Undiagnosed Psoriatic Arthritis In Patients With Plaque Psoriasis
|
N/A | |
| Completed |
NCT00760669 -
An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis Participants
|
Phase 4 | |
| Completed |
NCT00367237 -
Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)
|
Phase 3 | |
| Completed |
NCT00051623 -
A Study of the Safety and Effectiveness of Infliximab for the Treatment of Psoriatic Arthritis
|
Phase 3 | |
| Withdrawn |
NCT04680676 -
A Study to Test Different Doses of BI 730357 and Find Out Whether They Reduce Symptoms in People With Active Psoriatic Arthritis
|
Phase 2 | |
| Completed |
NCT03008590 -
Low Dose Naltrexone for Chronic Pain From Arthritis
|
Phase 2 | |
| Recruiting |
NCT05657847 -
Novel Complex Radiodiagnostics of Peripherial Arthropathies
|
||
| Completed |
NCT02875184 -
A Study of Apremilast Use and Effectiveness in Patients With Psoriatic Arthritis in The Netherlands
|