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Arthritis, Psoriatic clinical trials

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NCT ID: NCT02745080 Completed - Psoriatic Arthritis Clinical Trials

Efficacy of Secukinumab Compared to Adalimumab in Patients With Psoriatic Arthritis

EXCEED 1
Start date: April 3, 2017
Phase: Phase 3
Study type: Interventional

This was a randomized, double-blind, active controlled, multicenter, parallel-group study evaluating secukinumab monotherapy and adalimumab monotherapy in approximately 850 patients with active psoriatic arthritis (PsA) who are naïve to biologic therapy and are intolerant or having inadequate response to conventional disease modifying anti-rheumatic drugs (also known as non-biologic DMARDs).

NCT ID: NCT02721966 Completed - Clinical trials for Axial Psoratic Arthritis

Study of the Efficacy and Safety of Secukinumab in Participants With Active Psoriatic Arthritis With Axial Skeleton Involvement

MAXIMISE
Start date: October 3, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 150 mg or 300 mg in the management of axial manifestations in PsA patients who have failed to respond to at least 2 non-steroidal anti-inflammatory drugs (NSAIDs) over a 4-week period, according to assessment of spondyloarthritis international society (ASAS) recommendations for the treatment of axial spondyloarthritis (AxSpA).

NCT ID: NCT02719171 Completed - Clinical trials for Arthritis, Psoriatic

BI 655066/ABBV-066/Risankizumab Compared to Placebo in Patients With Active Psoriatic Arthritis

Start date: April 2016
Phase: Phase 2
Study type: Interventional

The overall purpose of this trial is to assess clinical efficacy and safety of different subcutaneous doses of BI 655066/ABBV-066/risankizumab in adult patients with psoriatic arthritis in order to select doses for further clinical trials.

NCT ID: NCT02714322 Completed - Psoriasis Clinical Trials

MYL-1401A Efficacy and Safety Comparability Study to Humira®

Start date: June 2015
Phase: Phase 3
Study type: Interventional

To assess the equivalence of MYL-1401A to Humira® with regards to efficacy in subjects with moderate-to-severe chronic plaque psoriasis

NCT ID: NCT02662985 Completed - Psoriatic Arthritis Clinical Trials

Study of Power Doppler Ultrasound (PDUS) to Measure Response of Secukinumab Treatment in Patients With Active Psoriatic Arthritis (PsA)

PDUS
Start date: August 22, 2016
Phase: Phase 3
Study type: Interventional

This study was designed to leverage the sensitivity of ultrasonography available in clinical practice setting to better describe the time course of response to secukinumab (150 mg and 300 mg) on joint synovitis and enthesitis in PsA patients with an inadequate response to non-biologic DMARDs. PDUS changes in joint synovitis will be assessed using the global Outcome Measures in Rheumatology (OMERACT)-European League against Rheumatism (EULAR) synovitis score (GLOESS) and changes in joint enthesitis were assessed using the OMERACT enthesitis score.

NCT ID: NCT02627768 Completed - Psoriatic Arthritis Clinical Trials

A Study on Assessment of STELARA and Tumor Necrosis Factor Alpha Inhibitor Therapies in Participants With Psoriatic Arthritis

PsaBio
Start date: December 17, 2015
Phase:
Study type: Observational

The purpose of this study is to evaluate treatment retention in psoriatic arthritis participants with STELARA or tumor necrosis factor alpha inhibitor (TNFi) therapies in relation to effectiveness, safety, benefit/risk and to examine clinical response.

NCT ID: NCT02605642 Completed - Clinical trials for Rheumatoid Arthritis

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade

PERSIST
Start date: September 10, 2015
Phase:
Study type: Observational

To assess persistence of CT-P13 in patients with Rheumatoid Diseases (Rheumatoid arthritis [RA], ankylosing spondylitis [AS], and psoriatic arthritis [PsA]) who are naïve to biologics or are switching from stable Remicade to CT-P13. The main objectives of the study are: - To evaluate real-life drug persistence in RA, AS, and PsA patients who are either initiated with CT-P13 as their first biologic, or who are switched from stable Remicade - To characterise the patient populations and drug usage patterns of RA, AS, and PsA patients who are either initiated with CT-P13 as their first biologic, or who are switched from stable Remicade - To assess the safety of CT-P13 in RA, AS, and PsA patients who are either initiated with CT-P13 as their first biologic, or who are switched from stable Remicade for up to 2 years

NCT ID: NCT02598739 Completed - Psoriatic Arthritis Clinical Trials

Evaluation of the Effectiveness of Resistance Training in Patients With Psoriatic Arthritis

PSA
Start date: May 2014
Phase: N/A
Study type: Interventional

The aim of this study was to assess the effectiveness of resistance training in improving functional capacity, muscle strength, quality of life and disease activity in patients with PSA.

NCT ID: NCT02584855 Completed - Psoriatic Arthritis Clinical Trials

A Long-Term Efficacy and Safety Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis

SPIRIT P3
Start date: September 14, 2015
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to evaluate the safety and long-term efficacy of ixekizumab compared to placebo in participants with active psoriatic arthritis.

NCT ID: NCT02556034 Completed - Clinical trials for Rheumatoid Arthritis

Assessment of Tender & Swollen Joints Count Score Performed by a Rheumatologist And Rheumatology Nurses in Patients With RA and PsA.

APRAN
Start date: September 2015
Phase:
Study type: Observational

This study will establish a comparison in follow-up care of 100 patients between Health Care Practitioners, more specifically the rheumatologist and a trained nurse. The study objective is to show consistency of evaluation between two different health care professionals, a physician and a nurse.