The Effect of AyuFlex® Supplementation on Joint Health

Status Completed

Clinical Trial Summary

The purpose of this 12-week, prospective study is to determine the effects of oral supplementation with AyuFlex® (an over-the-counter dietary supplement) on joint mobility, joint comfort and functional capacity in healthy overweight subjects.

Clinical Trial Description

This interventional study is a 12-week, randomized, double-blind, placebo and dose-response controlled clinical trial (in 3 parallel groups) of male and female subjects without active osteoarthritis of the knee to be recruited at a single investigational center in the U.S. A two-week placebo lead-in period will precede the study to enhance statistical power. One-hundred and five (105) overweight, apparently healthy subjects, pre-screened using health history questionnaires, vital signs, blood work and a standardized lower extremity exercise performance test will be randomized to one of three groups for 84 days: placebo, AyuFlex1 (500 mg/d) or AyuFlex2 (1000 mg/d). AyuFlex is an organic, non-GMO, over-the-counter joint health product derived from the edible fruits of Terminalia chebula. ;

Study Design

Related Conditions & MeSH terms

Arthralgia

Clinical Trial Details

NCT number	NCT02589249
Study type	Interventional
Source	The Center for Applied Health Sciences, LLC
Contact
Status	Completed
Phase	N/A
Start date	November 2015
Completion date	February 7, 2017

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