Arterial Occlusive Diseases Clinical Trial
Official title:
Comparative Study Between Systemic Analgesia and Continuous Sciatic Nerve Block in Patients With Chronic Obstructive Arterial Disease and Ischemic Pain in Lower Limbs
This project is one of four components of a thematic project that aims to evaluate the use
of ultrasound in regional blocks, called "Use of ultrasound in regional blocks and
injections for the treatment of acute and chronic pain."
It will evaluate quantitative and qualitative control of ischemic pain in the lower limbs in
patients with peripheral arterial occlusive disease through continuous sciatic nerve block
by perineural catheter, popliteal approach, compared to systemic analgesia based on opioids.
BACKGROUND: Peripheral arterial occlusive disease (PAOD) commonly evolves with intense
ischemic pain in the lower limbs, which is hard to control with systemic analgesics, and
continuous regional anesthesia may be an alternative, with adequate analgesia and lower
incidence of side effects.
OBJECTIVES: evaluate qualitative and quantitative pain control, incidence of adverse effects
and operative results in patients with PAOD undergoing continuous anesthetic blockade of the
sciatic nerve by perineural catheter compared to systemic analgesia based on opioids and
adjuvant medications.
METHODS: It is a randomized clinical trial, covered for evaluators. It will include 56
patients with PAOD Fontaine IV, with pain by the presence of ulcerations located on foot. A
group will be submitted to continuous regional anesthesia of sciatic nerve through
perineural catheter and another group will have its pain control through patient controlled
analgesia device with intravenous fentanyl. The primary dependent variable will be pain,
through the numerical pain scale.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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