Clinical Trials Logo
  1. Home
  2. Arterial Occlusive Diseases
  3. NCT00282646

Safety and Feasibility Study of Autologous Bone Marrow Cell Transplantation in Patients With Peripheral Arterial Occlusive Disease (PAOD)

Arterial Occlusive Diseases Clinical Trial

Official title:
(Intraarterial Progenitor Cell Transplantation of Bone Marrow Mononuclear Cells for Induction of Neovascularization in Patients With Peripheral Arterial Occlusive Disease)

Clinical Trial Summary

Patients with peripheral artery disease, stage III or IV who are not candidates for interventional or operative therapy should be treated with intraarterial progenitor cell therapy (autologous bone marrow cells) in a randomized, placebo controlled trial.

Clinical Trial Description

Main goal: Improvement of limb perfusion (Ankle brachial index). Secondary aims: Reduction of pain Reduction of Ulcer size Walking distance Improvement in tissue oxygenation (TCO2) Minor or major amputation ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00282646
Study type Interventional
Source Johann Wolfgang Goethe University Hospital
Contact
Status Completed
Phase Phase 2
Start date October 2005
Completion date March 2011
View Details
See also
  Status Clinical Trial Phase
Completed NCT03724279 - Crossing Atheroma or Thrombus With ByCross Device for Revascularization of Peripheral Arteries of Diameter ≥ 3mm N/A
Recruiting NCT04390672 - Multivessel TALENT N/A
Not yet recruiting NCT02841488 - Ischemic Pain Control With Analgesic Methods Clinical Trial Phase 3
Completed NCT00371371 - Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI) Phase 1/Phase 2
Completed NCT00209443 - A Safety and Efficacy Clinical Study to Evaluate the Narrowing of the Aorto-iliac Arteries While Using Gadodiamide Phase 3
Completed NCT00174759 - CASPAR : Clopidogrel and Acetyl Salicylic Acid in Bypass Surgery for Peripheral ARterial Disease Phase 3
Completed NCT00000539 - Arterial Disease Multifactorial Intervention Trial (ADMIT) Phase 3
Recruiting NCT04089943 - The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD N/A
Recruiting NCT04343209 - Ammonia N-13 Myocardial Blood Flow Absolute Quantification by PET in Patients With Known or Suspected CAD (Ammonia MAP)
Not yet recruiting NCT05930145 - Results of the Use of Two Stentrievers Simultaneosly Compared With One as a Primary Treatment in Acute Ischemic Stroke N/A
Recruiting NCT04142021 - Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)
Completed NCT03253692 - Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)
Active, not recruiting NCT04624854 - Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD) Phase 4
Active, not recruiting NCT02921230 - Trial Comparing ELUVIA Versus Bare Metal Stent in Treatment of Superficial Femoral and/or Proximal Popliteal Artery N/A
Recruiting NCT02593994 - IRIS-Onyx Cohort in the IRIS-DES Registry
Completed NCT02008097 - Clinical Benefits of B-Flow Ultrasound N/A
Terminated NCT01462721 - The eSVS® Mesh Randomized Post-Market Study N/A
Not yet recruiting NCT04956523 - Preliminary Tissue Monitoring During Endovascular Intervention Study
Recruiting NCT05616104 - FLEX FIRST Registry Research Protocol
Not yet recruiting NCT04175197 - LegDeb2 Global Registry for Use of Legflow in Peripheral Arteries