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Safety and Feasibility Study of Autologous Bone Marrow Cell Transplantation in Patients With Peripheral Arterial Occlusive Disease (PAOD)

Arterial Occlusive Diseases Clinical Trial

Official title:
(Intraarterial Progenitor Cell Transplantation of Bone Marrow Mononuclear Cells for Induction of Neovascularization in Patients With Peripheral Arterial Occlusive Disease)

Clinical Trial Summary

Patients with peripheral artery disease, stage III or IV who are not candidates for interventional or operative therapy should be treated with intraarterial progenitor cell therapy (autologous bone marrow cells) in a randomized, placebo controlled trial.

Clinical Trial Description

Main goal: Improvement of limb perfusion (Ankle brachial index). Secondary aims: Reduction of pain Reduction of Ulcer size Walking distance Improvement in tissue oxygenation (TCO2) Minor or major amputation ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00282646
Study type Interventional
Source Johann Wolfgang Goethe University Hospital
Contact
Status Completed
Phase Phase 2
Start date October 2005
Completion date March 2011
View Details
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