Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates

Arterial Hypotension Clinical Trial

Official title: Effect of Dobutamine as Compared to Dopamine on Cerebral Oxygenation, Mean Arterial Pressure and Cerebral Hemodynamics in Term and Preterm Neonates With Arterial Hypotension

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to examine the effects of Dobutamine as compared to Dopamine in term and preterm neonates with arterial hypotension on cerebral and renal oxygenation, fractional tissue oxygen extraction, mean arterial blood pressure and cardiac output.

The investigators hypothesize that Dopamine has a stronger effect on blood pressure than Dobutamine but Dobutamine has a stronger effect on cerebral oxygenation and cardiac output than Dopamine.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Arterial Hypotension
• Hypotension

• NCT number: NCT01427686
• Study type: Interventional
• Source: University of Ulm
• Status: Active, not recruiting
• Phase: Phase 4
• Start date: June 2011
• Completion date: December 2016