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Arterial Fibrosis clinical trials

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NCT ID: NCT04177251 Completed - Clinical trials for Idiopathic Pulmonary Fibrosis

Cardiovascular Fibrosis in Idiopathic Pulmonary Fibrosis

CardioIPF
Start date: October 21, 2019
Phase:
Study type: Observational

Fibroproliferative diseases, including pulmonary, cardiac and vascular fibrosis share common pathogenetic mechanisms. Furthermore, cardiovascular comorbidities are frequently found in patients with IPF. However, the prevalence of cardiac and vascular fibrosis in patients with IPF have yet to be determined. Main Purpose of this study is to evaluate, with non-invasive methods (echocardiogram, endothelial function and pulse wave velocity) and blood biomarkers (galectins-3, osteopontin, periostin and pro-BNP), the presence of vascular fibrosis (vascular rigidity and endothelial function) and cardiac fibrosis (prevalence of HFpEF - Heart Failure with Preserved Ejection Fraction) in patients with idiopathic pulmonary fibrosis (IPF), compared to healthy controls.