Dysrhythmias During General Anesthesia in Children

Status Completed

Clinical Trial Summary

To describe the types and incidence of cardiac dysrhythmias that occur under anesthesia in the present anesthesia environment.

Clinical Trial Description

It is unclear what the current state of anesthesia associated dysrhythmias is in the pediatric population. This was last investigated retrospectively in 1992 when the predominant volatile agent used for inhalation induction was halothane. Sevoflurane was approved by the Food and Drug Administration in 1995. Since that time, Sevoflurane has displaced halothane as the agent of choice for inhalation induction and has relegated halothane to be used in a narrow niche which primarily involves patients with very specific congenital heart diseases. It has been described that halothane has a larger proarrhythmic effect than sevoflurane for ventricular dysrhythmias. With the transition from the halothane to the sevoflurane era, a reassessment of the incidence and types of dysrhythmias occurring in non-cardiac pediatric patients is important. ;

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

Arrhythmias, Cardiac

Clinical Trial Details

NCT number	NCT00715390
Study type	Observational
Source	Children's Hospital of Philadelphia
Contact
Status	Completed
Phase	N/A
Start date	October 2004
Completion date	August 2006

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