Menoupausal Symptoms and Aromatherapy

Aromatherapy Clinical Trial

Official title:

Menoupausal Symptoms and Aromatherapy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05677698
• Other study ID #: Karatayhfz
• Status: Completed
• Phase: N/A
• Start date: December 27, 2022
• Est. completion date: February 27, 2023

Study information

• Verified date: November 2022
• Source: KTO Karatay University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Aromatherapy is "highly distilled herbs distilled to take advantage of their therapeutic properties".

is the science of using concentrated essential oils or essences".Essential oils or essences are obtained from various parts of plants (root, leaves, flowers, bark, fruit) and used therapeutically for physical and psychological well-being. The fact that aromatherapy is a noninvasive procedure and its ease of use allows for widespread use of aromatherapy. Aromatic oils can be applied in four basic ways. These include topical (tap, compress, or bath), internal (mouthwash, vaginal, or anal suppository), oral (with capsules or reconstitution in honey, alcohol, or diluent), and inhalation (direct or indirect, with or without steam, inhalation). ). Essential oils, which can be applied in various ways, can directly reach the neocortex part of the brain through connections extending from the limbic system to the hypothalamus via scent.

Description:

As a result of the effect of aromatic oils on the central nervous system, relaxation, sedation or stimulating effects occur and the information flow reaching the brain with the stimulation of the central nervous system.

Thanks to this, the energy blockage in the body is broken and as a result, energy is released. With the balanced distribution of the energy flow to the relevant organs, the healing process is supported, and physical and mental well-being emerges . Aromatherapy is used in many health fields as well as women's health. Menopause is a process in which physiological, psychological and hormonal changes occur in the life of all women . The World Health Organization defines menopause as "the permanent cessation of menstruation with loss of ovarian activity" . In addition to physical symptoms such as hot flashes, sweating, headache, low libido, fatigue, sleep disorders, palpitations, which occur as a result of the decrease in estrogen and progesterone hormone secretion and its end over time, psychological symptoms such as anxiety, depression and mood disorders are frequently encountered . Due to the increase in the number of women in the menopausal period in the world, it is important to reduce menopausal complaints and improve women's health.Studies have shown that aromatherapy is a complementary method used in a wide variety of situations to reduce physiological and psychological symptoms . It is stated that menopausal symptoms decrease in women who smell lavender aroma during menopause . It is important that the symptoms seen during menopause, which is an important part of a woman's life, are reduced and that women can spend this process more comfortably. While the age at menopause is in the range of 50-51 years worldwide, it is reported that the age of menopause in our country is between the ages of 47-49 . From this point of view, women spend about one third of their lives during and after menopause. The trend towards traditional and complementary medicine is increasing day by day in our country. However, in addition to the widespread use of aromatherapy in the world, aromatherapy practices are not common in our country. Diluted and ready-to-use forms of aromatic oils are not only available in pharmacies and herbalists, but also a method that people are curious about and want to use. The fact that the cost of ready-to-use aromatic oils is cheaper than drugs and easily accessible will provide women with a treatment option in the light of new evidence in line with the conduct of the study. In studies in the literature, it is stated that lavender, rose, geranium, and citrus oils are massaged to women in the menopausal period and provide mental and physical relaxation. Therefore, in our study, the use of Peppermint and Lemon oils to reduce the symptoms of menopausal women and increase their psychosocial well-being. is planned. Peppermint (Mentha Piperita) oil has analgesic, immune system strengthening, antispasmodic, antipyretic, anti-nausea and vomiting, anesthetic, helps concentration, increases self-confidence and creative thoughts, and Lemon (Citrus Lemon) oil is analgesic, immune-enhancing, antipyretic. It is thought that it can help relieve the psychological and physiological complaints of women in the menopausal period due to its properties such as helping constipation, reducing nausea and vomiting, increasing sleep quality, relieving stress and antidepressant. For this reason, it is planned to use Peppermint and Lemon oils in our study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 90
• Est. completion date: February 27, 2023
• Est. primary completion date: January 30, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 45 Years to 65 Years

Eligibility

Inclusion Criteria:

• Experiencing at least 1 of the menopausal symptoms (self-report),

• No respiratory disease such as asthma, bronchitis (self-report),

• Not allergic to the oils to be used (self-report),

Exclusion Criteria:

• Not experiencing menopausal complaints,

• Those who do not want to participate in the research

Related Conditions & MeSH terms

• Aromatherapy

Intervention

Other:
• Lemon oil
Lemon oil with massage
• peppermint oil
peppermint oil with massage
• Almond oil
Almond oil massage

Locations

Country	Name	City	State
Turkey	KTO Karatay University	Konya

Sponsors (1)

Lead Sponsor	Collaborator
KTO Karatay University

Country where clinical trial is conducted

Turkey, 

References & Publications (23)

Abbaspoor Z, Siahposh A, Javadifar N, Faal Siahkal S, Mohaghegh Z, Sharifipour F. The Effect of Citrus Aurantium Aroma on the Sleep Quality in Postmenopausal Women: A Randomized Controlled Trial. Int J Community Based Nurs Midwifery. 2022 Apr;10(2):86-95. doi: 10.30476/IJCBNM.2021.90322.1693. — View Citation

Bansal R, Aggarwal N. Menopausal Hot Flashes: A Concise Review. J Midlife Health. 2019 Jan-Mar;10(1):6-13. doi: 10.4103/jmh.JMH_7_19. — View Citation

Cramer H, Peng W, Lauche R. Yoga for menopausal symptoms-A systematic review and meta-analysis. Maturitas. 2018 Mar;109:13-25. doi: 10.1016/j.maturitas.2017.12.005. Epub 2017 Dec 6. — View Citation

Darsareh F, Taavoni S, Joolaee S, Haghani H. Effect of aromatherapy massage on menopausal symptoms: a randomized placebo-controlled clinical trial. Menopause. 2012 Sep;19(9):995-9. doi: 10.1097/gme.0b013e318248ea16. — View Citation

Dos Reis Lucena L, Dos Santos-Junior JG, Tufik S, Hachul H. Lavender essential oil on postmenopausal women with insomnia: Double-blind randomized trial. Complement Ther Med. 2021 Jun;59:102726. doi: 10.1016/j.ctim.2021.102726. Epub 2021 Apr 24. — View Citation

El Khoudary SR, Greendale G, Crawford SL, Avis NE, Brooks MM, Thurston RC, Karvonen-Gutierrez C, Waetjen LE, Matthews K. The menopause transition and women's health at midlife: a progress report from the Study of Women's Health Across the Nation (SWAN). Menopause. 2019 Oct;26(10):1213-1227. doi: 10.1097/GME.0000000000001424. — View Citation

Es-Haghee S, Shabani F, Hawkins J, Zareian MA, Nejatbakhsh F, Qaraaty M, Tabarrai M. The Effects of Aromatherapy on Premenstrual Syndrome Symptoms: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Evid Based Complement Alternat Med. 2020 Dec 21;2020:6667078. doi: 10.1155/2020/6667078. eCollection 2020. — View Citation

Farahani MA, Afsargharehbagh R, Marandi F, Moradi M, Hashemi SM, Moghadam MP, Balouchi A. Effect of aromatherapy on cancer complications: A systematic review. Complement Ther Med. 2019 Dec;47:102169. doi: 10.1016/j.ctim.2019.08.003. Epub 2019 Aug 5. — View Citation

Gözüyesil E, Baser M. 2016.'' Menopozal dönemde yasanan vazomotor yakinmalarin günlük yasam aktiviteleri üzerine etkisi'', Anadolu Hemsirelik ve Saglik Bilimleri Dergisi, 19(4):1-8.

Gurler M, Kizilirmak A, Baser M. The Effect of Aromatherapy on Sleep and Quality of Life in Menopausal Women with Sleeping Problems: A Non-Randomized, Placebo-Controlled Trial. Complement Med Res. 2020;27(6):421-430. doi: 10.1159/000507751. Epub 2020 Jun 9. — View Citation

Hur MH, Yang YS, Lee MS. Aromatherapy massage affects menopausal symptoms in korean climacteric women: a pilot-controlled clinical trial. Evid Based Complement Alternat Med. 2008 Sep;5(3):325-8. doi: 10.1093/ecam/nem027. — View Citation

Johnson A, Roberts L, Elkins G. Complementary and Alternative Medicine for Menopause. J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X19829380. doi: 10.1177/2515690X19829380. — View Citation

Kazemzadeh R, Nikjou R, Rostamnegad M, Norouzi H. Effect of lavender aromatherapy on menopause hot flushing: A crossover randomized clinical trial. J Chin Med Assoc. 2016 Sep;79(9):489-92. doi: 10.1016/j.jcma.2016.01.020. Epub 2016 Jul 4. — View Citation

Lee J, Han Y, Cho HH, Kim MR. Sleep Disorders and Menopause. J Menopausal Med. 2019 Aug;25(2):83-87. doi: 10.6118/jmm.19192. Epub 2019 Aug 5. Erratum In: J Menopausal Med. 2019 Dec;25(3):172. — View Citation

Nikjou R, Kazemzadeh R, Asadzadeh F, Fathi R, Mostafazadeh F. The Effect of Lavender Aromatherapy on the Symptoms of Menopause. J Natl Med Assoc. 2018 Jun;110(3):265-269. doi: 10.1016/j.jnma.2017.06.010. Epub 2017 Aug 18. — View Citation

Parry BL. Depressive history as a major predictor of postmenopausal depressive symptoms. Menopause. 2022 Jul 1;29(7):763-764. doi: 10.1097/GME.0000000000002027. No abstract available. — View Citation

Sanchez-Vidana DI, Ngai SP, He W, Chow JK, Lau BW, Tsang HW. The Effectiveness of Aromatherapy for Depressive Symptoms: A Systematic Review. Evid Based Complement Alternat Med. 2017;2017:5869315. doi: 10.1155/2017/5869315. Epub 2017 Jan 4. — View Citation

Santoro N, Epperson CN, Mathews SB. Menopausal Symptoms and Their Management. Endocrinol Metab Clin North Am. 2015 Sep;44(3):497-515. doi: 10.1016/j.ecl.2015.05.001. — View Citation

Taavoni S, Darsareh F, Joolaee S, Haghani H. The effect of aromatherapy massage on the psychological symptoms of postmenopausal Iranian women. Complement Ther Med. 2013 Jun;21(3):158-63. doi: 10.1016/j.ctim.2013.03.007. Epub 2013 Apr 16. — View Citation

Tanvisut R, Traisrisilp K, Tongsong T. Efficacy of aromatherapy for reducing pain during labor: a randomized controlled trial. Arch Gynecol Obstet. 2018 May;297(5):1145-1150. doi: 10.1007/s00404-018-4700-1. Epub 2018 Feb 3. — View Citation

Taskin L, editör. Dogum ve kadin sagligi hemsireligi. Genisletilmis XIII. Baski. Ankara: Akadmisyen Tip Kitabevi; 2019. p. 671-687

Tsai J, Chung YC, Chen FP, Yeh ML. [Effect of Aromatherapy on Menopausal Symptoms, Heart Rate Variability, and Sleep Quality in Women]. Hu Li Za Zhi. 2020 Feb;67(1):44-54. doi: 10.6224/JN.202002_67(1).07. Chinese. — View Citation

Türkiye Istatistik Kurumu. Istatistiklerle kadin, 2019. Türkiye Istatistik Kurumu Haber Bülteni. Sayi: 33732 Yayin Tarihi: 06.03.2020 1-5.

* Note: There are 23 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Menopause Symptoms Evaluation Scale	The original name of the scale is Menopause Rating Scale (MRS). The menopausal symptom rating scale (MSDS) was developed by Schneider et al. (2002) to measure the severity of menopausal symptoms. It was adapted into Turkish by Gürkan (2005). Menopause symptom assessment scale (MSDS) consists of 11 items. It is a Likert-type scale, and each item has options such as "None (0)", "Mild (1)", "Moderate (2)", "Severe (3)" and "Very Severe (4)". The total score of the scale is calculated by calculating the scores given for each item. A minimum of 0 points and a maximum of 44 points can be obtained from the scale. The increase in the total score obtained from the scale indicates the increase in the severity of the complaints. The Cronbach Alpha coefficient of the scale is 0.84.	1 year

External Links

•   World Health Organization (1981). Research on the menapouse. Available date: 16.08.2022