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Clinical Trial Summary

Expiratory flow limitation (EFL) is defined as a dynamic condition that expiratory flow cannot be further increased with higher expiratory driving pressure. Under mechanical ventilation, it can cause intrinsic positive end-expiratory pressure (PEEP) and dynamic hyperinflation, and be associated with worse clinical outcome. The detection of EFL however needs special maneuvers and offline analysis of flow-volume curves, which are infeasible in routine practice and cannot be used during real-time monitoring. The investigators propose a new and simple approach using flow derived parameters to detect EFL in real time without needing any intervention.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03215316
Study type Observational
Source St. Michael's Hospital, Toronto
Contact Laurent Brochard
Phone 416-864-5686
Email brochardl@smh.ca
Status Recruiting
Phase N/A
Start date September 1, 2017
Completion date September 2019

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