Different Menstrual Cycle in Eating Behavior Following Resistance Exercise

Appetitive Behavior Clinical Trial

Official title:

The Effects of Resistance Exercise on Appetite Control, Food Reward, and Energy Intake in Different Menstrual Cycles

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06208475
• Other study ID #: 202303HM002
• Status: Recruiting
• Phase: N/A
• Start date: August 1, 2023
• Est. completion date: July 2024

Study information

• Verified date: January 2024
• Source: National Taiwan Normal University
• Contact: Hung-Wen Liu, Ph.D.
• Phone: +886 0277496863
• Email: hwliu[@]ntnu.edu.tw
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study aims to provide insights into how menstrual cycle phases impact appetite responses to resistance exercise in young women. Healthy young women will participate in four trials: the exercise session in the follicular phase, the exercise session in the luteal phase, the control session in the follicular phase, and the control session in the luteal phase. Various measurements will be taken, including subjective appetite perceptions, appetite hormones, food preferences, lactate levels, estradiol levels, progesterone levels, and energy intake.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 16
• Est. completion date: July 2024
• Est. primary completion date: March 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 20 Years to 30 Years

Eligibility

Inclusion Criteria:

• Age: 20-30
• Healthy female with normal menstruation
• Weight stable for at least 6 months

Exclusion Criteria:

• Overweight (BMI > 30 kg/m^2 or body fat > 30%)
• Hypertension (> 140/90 mmHg)
• Cardiovascular disease, cancer or other chronic diseases

Related Conditions & MeSH terms

• Appetitive Behavior
• Energy Balance
• Food Reward
• Menstruation

Intervention

Other:
• Resistance exercise
Resistance exercises in the following order: squat, bench press, deadlift. Each exercise consisted of 3 sets with 7 repetitions, using a load of 70% 1RM with 120sec of rest between sets.

Locations

Country	Name	City	State
Taiwan	National Taiwan Normal University	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan Normal University

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Subjective appetite	The appetite perceptions are obtained through a 0-100 mm visual analog scale. The variables assessed include perceptions of hunger (i.e., "How hungry do you feel?"), satisfaction (i.e., "How satisfied do you feel?"), fullness (i.e., "How full do you feel?"), prospective food consumption (i.e., "How much do you think you can eat?"), and nausea (i.e., "How nauseous do you feel?"), with 0 indicating "not at all" and 100 signifying "extremely.".	4 hours during each study intervention
Primary	Change in acyl-Ghrelin	acyl-Ghrelin in pg/mL	4 hours during each study intervention
Primary	Change in total-Ghrelin	total-Ghrelin in pg/mL	4 hours during each study intervention
Primary	Change in PYY	PYY in pg/mL	4 hours during each study intervention
Primary	Change in active-GLP-1	active-GLP-1 in pg/mL	4 hours during each study intervention
Primary	Change in total-GLP-1	total-GLP-1 in pg/mL	4 hours during each study intervention
Primary	Change in lactate	insulin in mmol/L	4 hours during each study intervention
Secondary	Explicit liking	A visual analog scale ranging from 0 to 100 mm is utilized to evaluate the question, "How pleasant would it be to taste some of this food now?" with 0 indicating "not at all" and 100 signifying "extremely."	4 hours during each study intervention
Secondary	Explicit wanting	A visual analog scale ranging from 0 to 100 mm is utilized to evaluate the question, "How much do you want some of this food now?" with 0 indicating "not at all" and 100 signifying "extremely."	4 hours during each study intervention
Secondary	Implicit wanting	Participants are given a set of food image pairs and are asked to select their preference by answering the question, "Which food do you desire the most at the moment?". The implicit wanting calculation involves further consideration of response time data based on preference choices using a standardized equation.	4 hours during each study intervention
Secondary	Relative preference	Participants are given a set of food image pairs and are asked to select their preference by answering the question, "Which food do you desire the most at the moment?". The relative preference is the sum of the times each type of food is chosen, with a maximum value of 48 and a minimum value of 0.	4 hours during each study intervention
Secondary	Fat appeal bias	Fat preference (high or low) is calculated by subtracting the mean low-fat scores from the mean high-fat scores. Positive values suggest a preference for high-fat foods, while negative scores indicate a preference for low-fat or savory foods, and a score of 0 signifies an equal preference between fat content.	4 hours during each study intervention
Secondary	Taste appeal bias	Taste preference (savoury or sweet) is calculated by subtracting the mean savory scores from the mean sweet scores. Positive values suggest a preference for sweet foods, while negative scores indicate a preference for savory foods, and a score of 0 signifies an equal preference between taste categories.	4 hours during each study intervention
Secondary	Change in TG	TG in mg/dL	4 hours during each study intervention
Secondary	Change in glucose	glucose in mg/dL	4 hours during each study intervention
Secondary	Change in insulin	insulin in mU/L	4 hours during each study intervention
Secondary	Sex hormones	Sex hormones will be measured, such as estrogen and progesterone	4 hours during each study intervention
Secondary	Energy intake	Participants will be required to record their diet for the day before, the current day, and the day following the experiment.	3 days during each study intervention