Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults

Appetitive Behavior Clinical Trial

Official title:

Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03409497
• Other study ID #: 055-049
• Status: Completed
• Phase: N/A
• Start date: May 17, 2019
• Est. completion date: June 30, 2020

Study information

• Verified date: August 2019
• Source: Purdue University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Assess the impact of 100% grape juice with a meal on postprandial glycemic response and subsequent appetite, food intake and cognitive function.

Description:

Investigators earlier studies and published literature suggest that the phenolic content and strong flavor intensity of 100% Concord grape juice hold potential beneficial effects on blood sugar levels. Investigators aim to better understand the consumption of 100% grape juice with a meal modifies appetite and glycemia acutely and over the day using a 24 hour glucose monitor.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: June 30, 2020
• Est. primary completion date: October 28, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 25 Years to 60 Years

Eligibility

Inclusion Criteria:

• BMI between 25.0-34.9 kg/m2

• Willingness to eat all test foods

• Low consumer of tea and coffee, willingness to refrain from both during the 48 hours prior to test days and on the test day

• Fasting blood glucose below 6.1mmol/l via capillary finger-stick blood sample using a SureStep glucometer (Lifescan, Milpitas, CA)

Exclusion Criteria:

• Taking medications known to affect glycemia, lipid metabolism or appetite

• Body weight fluctuation of >5kg in the past 3 months

• Taking vitamin or other supplements

• Smokers

• Acute or Chronic disease

Related Conditions & MeSH terms

• Appetitive Behavior
• Glycemic Response

Intervention

Other:
• Concord Grape Juice
Concord Grape Juice
• Low flavonoid low essence beverage
Low flavonoid low essence beverage
• Low flavonoid beverage
Low flavonoid beverage

Locations

Country	Name	City	State
United States	Purdue University	West Lafayette	Indiana

Sponsors (2)

Lead Sponsor	Collaborator
Purdue University	Welch's Food Corporation

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change in blood glucose over 24 hours	samples taken every 5 minutes for 24 hours by a continuous glucose monitor	24 hours
Secondary	Appetite	Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on same day as grape juice intervention	24 hours