Clinical Trials Logo
  1. Home
  2. Appendicitis
  3. NCT05966454

Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF — CASA RELAX  

Appendicitis Clinical Trial

Official title:
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) Using Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR) -A Randomized Controlled Trial

Clinical Trial Summary

The purpose of this study is to demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis

Clinical Trial Description

This is a single center, randomized controlled trial to determine if decreasing the amount of antibiotics after appendicitis surgery can decrease the risk of adverse effects associated with antibiotics while at the same time ensuring participant safety. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05966454
Study type Interventional
Source University of California, San Francisco
Contact Lucy Kornblith, MD
Phone 628-206-6946
Email Lucy.Kornblith@ucsf.edu
Status Recruiting
Phase Phase 4
Start date June 6, 2023
Completion date June 30, 2025
View Details
See also
  Status Clinical Trial Phase
Completed NCT04529980 - Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis N/A
Withdrawn NCT03528343 - Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy Phase 1/Phase 2
Recruiting NCT03522233 - Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds
Recruiting NCT03380793 - A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis Phase 4
Recruiting NCT02108340 - Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis N/A
Terminated NCT02029781 - The Laparoscopic Appendicitis Score; a Multicenter Validation Study N/A
Completed NCT01356641 - Antibiotic Treatment Alone for Acute Simple Appendicitis in Children N/A
Completed NCT01515293 - Single Incision Versus Conventional Laparoscopic Appendectomy Phase 3
Completed NCT00913380 - Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT Phase 3
Terminated NCT00971438 - Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging N/A
Completed NCT00530998 - Minimally Invasive Surgery: Using Natural Orfices
Completed NCT00616616 - Single Incision Laparoscopy N/A
Completed NCT00195351 - Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Phase 4
Completed NCT02916134 - Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis N/A
Completed NCT04614649 - Right Iliac Fossa Treatment-Turkey Audit
Completed NCT04365491 - European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
Completed NCT03770897 - Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome N/A
Completed NCT02507674 - Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study
Active, not recruiting NCT01718275 - Non-operative Management of Early Appendicitis in Children
Terminated NCT01575028 - Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies Phase 2