a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Appendicitis

Appendicitis Clinical Trial

Official title:

Retrocaecal Appendicitis: Risk Factor for Perioperative Complications?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05315869
• Other study ID #: AppendicitisFNKV
• Status: Completed
• Start date: January 1, 2015
• Est. completion date: May 1, 2020

Study information

• Verified date: March 2022
• Source: Faculty Hospital Kralovske Vinohrady
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

A retrospective observational study investigating whether retrocecal appendicitis associated with worse operative and postoperative outcomes than non-retrocecal appendicitis.

Description:

Acute appendicitis is the most common cause of acute abdomen requiring acute surgery. The prevalence of the retrocaecal position of the appendix varies significantly between studies from 14 to 36%. Appendectomy of a retrocecal appendix is generally considered to be more demanding procedure than appendectomy of appendices in other positions. The aim of this study is to investigate whether retrocaecal appendicitis is associated with a higher rate of perioperative complications and delayed diagnosis when compared with the other positions.

A retrospective analysis of prospectively collected data of patients undergoing surgery for signs of acute appendicitis from January 2015 to April 2020 at the University Hospital Kralovske Vinohrady. Two groups of patients were be formed: the retrocaecal group and the non-retrocaecal group.

The following data were recorded: sex, age, body mass index, length of hospital stay, abdominal drain placement, length of surgery, surgical approach (laparoscopic, open or converted), operative finding (normal appendix or catarrhal, phlegmonous, gangrenous, or perforated appendicitis), position of the appendix (retrocaecal or non-retrocaecal positions), histopathological findings (acute inflammation, chronic inflammation, appendiceal tumour or normal appendix), 30-day postoperative complications, 30-day postoperative mortality, symptoms (abdominal pain, nausea, vomiting, diarrhoea, body temperature above 37 degrees celsius, urological complaints and gynaecological complaints), duration of symptoms (from onset to surgery), serious comorbidities and diabetes mellitus.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 754
• Est. completion date: May 1, 2020
• Est. primary completion date: April 1, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• All patients undergoing surgery for signs of acute appendicitis at the department of surgery of the University Hospital Kralovske Vinohrady between January 2015 to April 2020

Exclusion Criteria:

• Patients under 18 years of age

Related Conditions & MeSH terms

• Appendicitis
• Appendicitis Acute

Intervention

Procedure:
• Appendectomy
Surgical procedure for removal of the appendix

Locations

Country	Name	City	State
Czechia	Adam Whitley	Praha 3	Prague

Sponsors (1)

Lead Sponsor	Collaborator
Faculty Hospital Kralovske Vinohrady

Country where clinical trial is conducted

Czechia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of patient with postoperative complications	surgical site infections, postoperative ileus, bleeding, internal complications,	30 days after intervention (appendectomy)
Primary	Number of patient who undergo converted appendectomy	Conversion from laparoscopic to open appendectomy	during the surgery
Primary	Length of hospital stay	Length of hospital stay after the procedure in days	30 days after intervention (appendectomy)
Primary	Duration of procedure	Duration of appendectomy in minutes	Throughout the study period (1/2015-4/2020)