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Clinical Trial Summary

This study aims to compare antibiotic treatment versus surgery for patients with uncomplicated appendicitis.


Clinical Trial Description

The study will include patients aged 16 and over, with a first admission with right iliac fossa pain and a raised white cell count or C-reactive protein. Patients will be randomised electronically in a 1:1 ratio either to undergo emergency appendectomy or to receive intravenous antibiotics as an inpatient, until clinical and biochemical improvement is observed, followed by outpatient oral antibiotics. Those who have surgery will have 3 post-operative doses of intravenous antibiotics, unless perforation was identified at the time of surgery, in which case, microbiology will be contacted to advise regarding antibiotic choice and duration. Follow-up by telephone interview will be at 1 week, 1, 3 and 12-month intervals. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02916134
Study type Interventional
Source Beaumont Hospital
Contact
Status Completed
Phase N/A
Start date September 12, 2016
Completion date December 8, 2019

See also
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