Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis

Appendicitis Clinical Trial

Official title:

Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02108340
• Other study ID #: ?S 45/19-9-2013
• Status: Recruiting
• Phase: N/A
• First received: April 2, 2014
• Last updated: February 11, 2017
• Start date: September 2013
• Est. completion date: August 2017

Study information

• Verified date: February 2017
• Source: Hippocration General Hospital
• Contact: Konstantinos G. Toutouzas, MD, PhD
• Phone: 00306970801370
• Email: tousur[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will evaluate the use of microwave radiometry in a population of patients diagnosed with acute appendicitis and treated with appendectomy. The main purpose of the study is to report the results of microwave radiometry as a diagnostic tool in acute appendicitis and compare those results with the commonly used ultrasonography.

Description:

Patients diagnosed with acute appendicitis from the emergency department of Hippocration General Hospital and treated with appendectomy will be evaluated with microwave radiometry for changes in the temperature of the appendix before its removal.

Subsequently, the results of microwave radiometry for the patients confirmed by the histopathology report to have acute inflammation of the appendix, will be compared with those of the ultrasonography used for the diagnosis of acute appendicitis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: August 2017
• Est. primary completion date: July 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Clinical diagnosis of appendicitis

• Surgical removal of appendix

• Pathological confirmation of appendicitis

Exclusion Criteria:

Related Conditions & MeSH terms

• Appendicitis

Intervention

Procedure:
• Microwave radiometry
Microwave radiometry of the right lower quadrant in a room temperature of 20-24 degrees celsius, in order to record changes in the temperature of the inflamed appendix.

Locations

Country	Name	City	State
Greece	Hippocration General hospital	Athens	Attiki

Sponsors (1)

Lead Sponsor	Collaborator
Hippocration General Hospital

Country where clinical trial is conducted

Greece, 

References & Publications (4)

Arunachalam K, Maccarini PF, De Luca V, Bardati F, Snow BW, Stauffer PR. Modeling the detectability of vesicoureteral reflux using microwave radiometry. Phys Med Biol. 2010 Sep 21;55(18):5417-35. doi: 10.1088/0031-9155/55/18/010. — View Citation

Hassan AM, El-Shenawee M. Review of electromagnetic techniques for breast cancer detection. IEEE Rev Biomed Eng. 2011;4:103-18. doi: 10.1109/RBME.2011.2169780. Review. — View Citation

Toutouzas K, Grassos C, Drakopoulou M, Synetos A, Tsiamis E, Aggeli C, Stathogiannis K, Klettas D, Kavantzas N, Agrogiannis G, Patsouris E, Klonaris C, Liasis N, Tousoulis D, Siores E, Stefanadis C. First in vivo application of microwave radiometry in human carotids: a new noninvasive method for detection of local inflammatory activation. J Am Coll Cardiol. 2012 May 1;59(18):1645-53. doi: 10.1016/j.jacc.2012.01.033. — View Citation

Toutouzas K, Grassos H, Synetos A, Drakopoulou M, Tsiamis E, Moldovan C, Agrogiannis G, Patsouris E, Siores E, Stefanadis C. A new non-invasive method for detection of local inflammation in atherosclerotic plaques: experimental application of microwave radiometry. Atherosclerosis. 2011 Mar;215(1):82-9. doi: 10.1016/j.atherosclerosis.2010.12.019. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Appendix Temperature	Microwave radiometry will assess the temperature of the appendix for the patients diagnosed with appendicitis before they undergo surgical removal of the appendix.	Baseline