Appendicitis Clinical Trial
Official title:
Importance of Peritoneal Free Fluid Cultures in Both Perforated and Non-perforated Appendicitis
The purpose of this study is to evaluate the frequency of positive free fluid cultures in both perforated and non-perforated appendicitis. In addition predictors of positive free fluid cultures will be analyzed.
Prior to surgery, all patients will receive antibioprophylaxis. In case of free peritoneal
fluid, a sample is aspirated and sent for microbiology. A lavage with saline is not
necessary. The decision to start postoperative antibiotic is left at the discretion of the
surgeon. The decision to leave an abdominal drain is left at the discretion of the surgeon.
The use of a preoperative single dose administration of antibiotics has been extensively
studied and found beneficial in the prevention of SSI in appendicitis. However, the use of
continued postoperative antibiotics has barely been studied. The sparse evidence that exist
does not seem to support its systematic use. During appendectomy the surgeon frequently
encounters turbid free fluid, even in non-perforated appendicitis. It is common practice in
Belgium to continue antibiotic prophylaxis for 5 days after aspiration and lavage. Although
the aspect often seems purulent, it is unknown in what percentage this fluid is
contaminated. Also, it is unknown whether after aspiration and lavage intra-abdominal drains
are necessary.
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Observational Model: Cohort, Time Perspective: Prospective
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