Appendicitis Clinical Trial
Official title:
Double Blind Randomized Study of Morphine Analgesia in Patients With Acute Appendicitis
The purpose of the study is to evaluate morphine effect on pain reduction and diagnostic accuracy in patients admitted to emergency ward with the diagnosis of acute appendicitis.
Analgesic administration for pain control in patients with acute abdominal pain, regarding
acute appendicitis, is controversial. Despite the results previous studies indicating the
safeness of analgesic use in ED for acute abdominal pain, physicians still prefer to
postpone their use after performing surgical evaluations. Since many patients admitted to ED
are unlikely to receive prompt surgical consultation, many of them need pain relief to
prevent unnecessary suffering. On the other hand such pain relief must not interfere with
the diagnosis and treatment of patients and do not cause any complications. Morphine is a
common and effective analgesic which, if shown to have no effect on correct diagnosis of
acute abdomen, can be used for this purpose.
Thus we evaluated morphine effect on pain reduction and diagnostic accuracy in patients
admitted to ED with the diagnosis of acute appendicitis.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Supportive Care
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