Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis

Status Withdrawn

Clinical Trial Summary

This study evaluates the ability of contrast-enhanced ultrasound to improve the diagnosis of acute appendicitis in children compared to conventional ultrasound.

Clinical Trial Description

Acute appendicitis is the most common surgical emergency in children. Diagnostic evaluation for possible appendicitis frequently leads to imaging studies. Magnetic resonance imaging (MRI) and computed tomography (CT) are currently the gold-standard techniques for the diagnosis or exclusion of acute appendicitis. However, these methods not always immediately available; may require administration of intravenous contrast material with the potential for allergic reactions and nephrotoxicity; and, in the case of CT, requires the administration of ionizing radiation that is linked to the long-term development of radiation-induced cancers. The current study will evaluate a potentially safer, radiation-free diagnostic method for acute appendicitis, using contrast-enhanced ultrasound to provide a more accurate means of visualizing the appendix than conventional US imaging. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03295656
Study type	Interventional
Source	Boston Children’s Hospital
Contact
Status	Withdrawn
Phase	Phase 1
Start date	July 15, 2020
Completion date	July 15, 2020

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