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Appendicitis Acute clinical trials

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NCT ID: NCT05315869 Completed - Appendicitis Clinical Trials

a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Appendicitis

Start date: January 1, 2015
Phase:
Study type: Observational

A retrospective observational study investigating whether retrocecal appendicitis associated with worse operative and postoperative outcomes than non-retrocecal appendicitis.

NCT ID: NCT05310266 Completed - Surgery Clinical Trials

Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy

Start date: April 6, 2020
Phase: N/A
Study type: Interventional

Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.

NCT ID: NCT05219786 Completed - Appendicitis Acute Clinical Trials

Online Field Test of an Appendicitis Decision Support Tool

Start date: October 6, 2021
Phase: N/A
Study type: Interventional

After the recent publication of the CODA Trial comparing antibiotics and surgery for acute appendicitis, the investigators developed a comprehensive decision support tool. This tool will help patients understand the risks and benefits of each treatment and make a treatment decision. This study is an online randomized field test comparing the decision support tool to a control infographic and assessing it's affect on decisional outcomes, such as decisional conflict.

NCT ID: NCT05097118 Completed - Appendicitis Acute Clinical Trials

Surgical Site Infiltration Using Ketamine Versus Bupivacaine for Analgesia in Post-operative Appendectomy Operation

Start date: September 1, 2021
Phase: Early Phase 1
Study type: Interventional

surgical site infiltration using ketamine versus Bupivacaine for analgesia in post-operative Appendectomy operation by Ketamine versus Bupivacaine

NCT ID: NCT05095987 Completed - Appendicitis Acute Clinical Trials

Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children.

Start date: October 2, 2021
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the value and safety of discharge of a child to home care within 24 hours after laparoscopic appendectomy for uncomplicated appendicitis to reduce the impact on the child's psyche and need for hospitalisation. Baseline demographic data and intraoperative finding will be recorded. Parents are given a two-page questionnaire that is completed in three cycles (immediately after discharge, daily until the first control and immediately before the first control). All data will be statistically processed using descriptive statistics.

NCT ID: NCT05093660 Recruiting - Appendicitis Acute Clinical Trials

Diagnostic Importance of the Circulating Human Leucine-rich α-2-glycoprotein in Acute Appendicitis in Pediatric Patients

Start date: October 15, 2021
Phase:
Study type: Observational

Acute appendicitis is a common and potentially serious medical condition which can be difficult to diagnose, especially in pediatric patients. To help recognize patients with acute appendicitis, number of laboratory and radiological test are used. Previous research has shown that Circulating Human Leucine-rich α-2-glycoprotein (LGR1) in the blood can be elevated in pediatric patients with acute appendicitis. The aim of this research is to analyse whether LGR1 levels in saliva can be used as a less invasive diagnostic method in pediatric patients with suspected acute appendicitis.

NCT ID: NCT05070000 Completed - Appendicitis Acute Clinical Trials

Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold Standard.

Start date: January 1, 2016
Phase:
Study type: Observational

This study is a retrospective evaluation of all patients treated surgically for appendicitis over a period of 3 years at the Sint- Andries Hospital, Tielt. Belgium. The goal is to evaluate the value of ultrasound (US), computed tomography (CT) and laboratory testing in diagnosing acute appendicitis and to look for the possible impact on the treatment.

NCT ID: NCT04969133 Recruiting - Analgesia Clinical Trials

TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children

PABLO
Start date: July 30, 2021
Phase: N/A
Study type: Interventional

When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia. These techniques include local infiltration of the trocar wounds or transverse abdominal plane block (TAP block). In 2018, a position paper of the European Society of Pediatric Anaesthesiology advised for TAP block over local infiltration of the trocar wounds. However, there is no randomized study comparing both techniques in children. The aim of this study is to compare morphine consumption during the first 24 postoperative hours in children undergoing laparoscopic appendectomy and randomly allocated to either local infiltration of the trocar wounds or TAP block.

NCT ID: NCT04949659 Recruiting - Appendicitis Acute Clinical Trials

Low vs Medium Pressure Pneumoperitoneum

LoMePneu
Start date: September 27, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to asses whether the pressure used for the pneumoperitoneum during laparoscopic surgery in children affects their postoperative pain levels.

NCT ID: NCT04947748 Recruiting - Acute Appendicitis Clinical Trials

Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.