Clinical Trials Logo
  1. Home
  2. Apnea
  3. NCT04722276

Fraction of Oxygen on Induction of Anesthesia in Infants — PEEP  

Apnea Clinical Trial

Official title:
The Effect of Positive End-expiratory Pressure During Induction of General Anesthesia and Non-hypoxic Apnea Time in Infants: a Randomized Controlled Trials

Clinical Trial Summary

Invesetigators evaluated the effect of positive end-expiratory pressure during anaesthesia induction on nonhypoxic apnoea time in infants. Invesetigators assigned infants to a 7 cmH2O positive end expiratory pressure (PEEP) with fraction of inspired oxygen 80% or 0 cmH2O PEEP with fraction of oxygen 80% group. Anaesthesia was induced with 0.02 mg kg atropine, 5 mg kg thiopental sodium and 3 to 5% sevoflurane, and neuromuscular blockade with 0.6 mg kg rocuronium. Thereafter, 80% oxygen was provided via face mask with volume-controlled ventilation of 6 ml kg tidal volume, and either 7 cmH2O or no positive end-expiratory pressure. After 3 min of ventilation, the infants' trachea was intubated but disconnected from the breathing circuit, and ventilation resumed when pulse oximetry reached 95%.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04722276
Study type Interventional
Source Seoul National University Hospital
Contact
Status Completed
Phase N/A
Start date February 1, 2021
Completion date July 1, 2023
View Details
See also
  Status Clinical Trial Phase
Completed NCT02580526 - Comparison of Mask Ventilation Techniques in Patients Requiring General Anesthesia N/A
Completed NCT02627001 - Nu-Mask Intraoral Airway Device Versus Conventional Bag Valve Mask Ventilation Crossover Trial Phase 4
Recruiting NCT01825473 - Study of Erythromycin in GER-Associated Apnea of the Newborn N/A
Completed NCT02103777 - High Versus Low Dose of Caffeine for Apnea of Prematurity Phase 3
Completed NCT00950287 - Detection of Neonatal Bradycardia N/A
Recruiting NCT00382876 - Identifying the Relative Change in Ventilation in Newborns With Placement in Car Bed or Car Seat N/A
Completed NCT00369759 - An Epidemiological Study to Evaluate the RSV-Associated Lower Respiratory Track in Infections in Infants N/A
Completed NCT04084535 - Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea. N/A
Recruiting NCT02968797 - Clinical Comparative Study to Validate Performance of SafeSed Prototype Monitoring Endoscopy Under Sedation
Completed NCT02554110 - Peripheral Nerve Stimulation to Reduce Hypoxic Events N/A
Not yet recruiting NCT04366414 - Breathing Protocol in Breath-hold Divers N/A
Completed NCT05124093 - The Effect of High-flow Nasal Oxygen Flow Rate on Gas Exchange During Apnoea N/A
Recruiting NCT01994785 - Use of Capnography in EGD and Colonoscopy With Moderate Sedation. N/A
Completed NCT01435486 - Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants N/A
Completed NCT01852929 - Sleep Apnea and Visual Perceptual Skill Learning N/A
Completed NCT00389909 - Dosing Chart for Calculating the First Dose of Doxapram in Premature Infants Phase 4
Completed NCT00188968 - Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants. Phase 3
Not yet recruiting NCT05396274 - High Flow Nasal Oxygen Therapy Undergoing Colonoscopy N/A
Completed NCT02800213 - Ventilation Using a Bag Valve Mask With Supplemental External Handle N/A
Completed NCT02375230 - MRSOPA-Drills to Improve Mask Ventilation in the Delivery Room N/A