Apnea Clinical Trial
Official title:
Skeletal, Dental and Upper Airway Changes in Skeletal Class II Division 1 Patients With the Constricted Maxilla (8-14 Years Old) Treated With Twin Block and Hyrax, Evaluated Through Pressure Drop Experimental Analysis.
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least. But what if orthodontic treatment could help those patients to breathe better, with less effort? This research proposal aims to find out if the increase in the upper airway volume seen in some research results can be related to a decrease in respiratory effort and an improvement in the breathing capacity of those patients. In other words, if a tube shape is changed or if a tube is enlarged, would the airflow passing inside the tube change in velocity? Or would there be more air? Therefore, investigating the pressure/airflow, volume/lumen relation and its possible changes after mandibular repositioning and maxillary expansion in children will lead to a better understanding of how orthodontics could potentially affect the upper airway. Previous studies have reported a link between mandibular advancement appliances and maxillary appliances to an increase in the upper airway volume. However, more studies are needed to evaluate the relationship between the changes in the upper airway volume and actual airflow and respiratory capability. The airway volume measurement is important to, preliminary, state if there is an increase in the upper airway after orthodontic treatment. However a change in shape, even with the same volume, can affect the pressure and airflow. In this sense, the pressure drop analysis will allow an answer to those questions
Status | Recruiting |
Enrollment | 90 |
Est. completion date | December 1, 2025 |
Est. primary completion date | February 1, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 8 Years to 14 Years |
Eligibility | Inclusion Criteria: - children between the ages 8-14 years old (8-12 years old girls and 9-14 years old boys), presenting skeletal class II division 1 malocclusion with maxillary constriction Exclusion Criteria: - syndromic patients, previous ortho history, non-compliance, severe oral health issues (cavities, poor oral hygiene) |
Country | Name | City | State |
---|---|---|---|
Canada | University of Alberta | Edmonton | Alberta |
Lead Sponsor | Collaborator |
---|---|
University of Alberta |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Airflow | Airflow of the upper airway using pressure drop experimental analyzed using the CBCTs scans to print out the models of the upper airway. | 3 years | |
Secondary | Dental changes | Dental changes after orthodontic treatment. Measurements of the teeth in relation to several cranial based landmarks will be made to analyse teeth movements. Those measurements will be done using the CBCTs scans. | 3 years | |
Secondary | Skeletal changes | Skeletal changes after orthodontic treatment. Measurements of 29 landmarks inside the skull will be made to verify the changes related to bone. The CBCTs scans will be used. | 3 years |
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