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Apea of Prematurity clinical trials

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NCT ID: NCT01509248 Enrolling by invitation - Apea of Prematurity Clinical Trials

Population Pharmacokinetics and Metabolomics of Theophylline in Preterm Infants

Start date: May 2010
Phase: N/A
Study type: Observational

1. Population pharmacokinetics : The purpose of this study is - to investigate the population pharmacokinetics of theophylline in premature Korean infants and to assess the influence of demographic and clinical covariates. 2. Metabolomics : The purpose of this study are - to predict serum theophylline levels and to assess CYP1A2 activities in premature infants by analyzing urinary metabolites of theophylline - to examine which factors affect clearance of theophylline and CYP1A2 activity in premature infants