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Clinical Trial Summary

The term 'aortitis' refers to inflammation of the aorta. Aortitis is known to occur in a variety of vasculitides and connective tissue diseases, such as giant cell arteritis (GCA), Takayasu arteritis (TAK), rheumatoid arthritis, and spondyloarthropathies, among others. This study will establish a longitudinal cohort for these diseases.


Clinical Trial Description

This study will develop a longitudinal cohort of patients with different types of aortitis to systematically study the natural history, optimal treatments, and outcomes in this group of diseases. This will provide a resource for future studies and for identification of new biomarkers of aortitis for purposes of diagnosis, disease activity measurement, disease damage assessment, determination of disease states, and evaluation of treatment response. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03022331
Study type Observational
Source University of Pennsylvania
Contact
Status Completed
Phase
Start date December 4, 2017
Completion date September 1, 2019

See also
  Status Clinical Trial Phase
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Completed NCT01795456 - Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis N/A
Not yet recruiting NCT06271018 - TocILizumab in aorTitis in GCA (TILT)