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Defining Exercise Hemodynamics and Function After Transcatheter Aortic Valve Replacement (DEFINE-TAVR) Study. — DEFINE-TAVR  

Aortic Valve Stenosis Clinical Trial

Official title:
DEFINE-TAVR (Defining Exercise Hemodynamics and Function After Transcatheter Aortic Valve Replacement) Study

Clinical Trial Summary

The purpose of this study is to help understand how the replacement valve functions over time, both at rest and during exercise.

Clinical Trial Description

The objective of this single-center registry is to evaluate prosthetic valve hemodynamics and function over time in patients undergoing clinically indicated transcatheter aortic valve replacement (TAVR) for symptomatic severe aortic stenosis. Specific goals include: - Describe valve hemodynamics at rest (baseline, post-procedure, 30 days, 1 year) and with exercise (at 30 days and 1 year) after TAVR implantation to define valve function and hemodynamics over time. - Compare valve hemodynamics and function at rest and exercise between self-expanding and balloon expandable valves. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05567809
Study type Observational [Patient Registry]
Source Yale University
Contact Yousif Ahmad, MD
Phone 2037857990
Email yousif.ahmad@yale.edu
Status Recruiting
Phase
Start date October 25, 2022
Completion date October 2024
View Details
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