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Outcome, Recuperation and Hemodynamics in Aortic Stenosis — PROCARE-AS  

Aortic Valve Stenosis Clinical Trial

Official title:
PRognosis of Outcome and Recuperation of Cardiac Hemodynamic Function After Aortic Valve REplacement in Aortic Valve Stenosis

Clinical Trial Summary

Indication for aortic valve replacement (AVR) in aortic stenosis (AS) is currently based on the classical triad of clinical AS symptoms, estimation of AS severity, and cardiac repercussion at rest. However, presence of symptoms in elderly is often subjective and underreported, and cardiac function analysis at rest underestimates the true impact of the chronic afterload increase. This complicates the diagnosis and hampers timely aortic valve replacement therapy with an impact on prognosis and cardiac function recovery. Exercise imaging in AS may reveal underlying cardiac repercussion and symptoms at an earlier stage and therefore impact prognosis and cardiac function recovery after AVR. Therefore the principal objective of this study is to reveal the factors that determine clinical outcome and hemodynamic function recovery after AVR in AS.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05272020
Study type Interventional
Source Jessa Hospital
Contact Sarah Hoedemakers, MD
Phone +32498260617
Email sarahhoed@gmail.com
Status Recruiting
Phase N/A
Start date March 22, 2021
Completion date March 31, 2024
View Details
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