Aortic Valve Disease Clinical Trial
Official title:
Study on Optimal Treatment Strategy for Elderly Patients With High-risk Complex Aortic Valve Disease
Aortic valve disease (AVD) is the most common and age-related mortality in elderly patients with valvular heart disease (VHD). Although transcatheter aortic valve replacement (TAVR) has been recommended at a higher level in foreign guidelines, there are still many high-risk and severe elderly patients with VHD who have not received effective treatment because of many complications and untimely medical treatment. Different from Europe and the United States, the majority of patients with bicuspid aortic valve are in China, and the calcification is more serious. The current clinical evaluation system and treatment guidelines can not be effectively applied to the high-risk and complex elderly patients. Therefore, the investigators should train and set up a valvular heart disease team, explore the technical difficulties of TAVR treatment in such patients, establish emergency TAVR operation mechanism, build a clinical evaluation system for high-risk and complex elderly patients with aortic valve disease in China, evaluate the curative effect periodically and further optimize the treatment strategy, so as to improve the quality of life and the meaning of life cycle of elderly patients with VHD in China Great significance.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04149600 -
Identification of Genetic Causes of Calcific Aortic Valve Disease
|
||
Recruiting |
NCT06001489 -
The Effects of 360-degree Virtual Reality on Pre-procedural Anxiety in Patients Awaiting Elective Cardiac Surgery Involving a Sternotomy
|
N/A | |
Not yet recruiting |
NCT04430972 -
Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure)
|
||
Completed |
NCT02467062 -
Implementation of Non-size Markers Derived From 4D Flow MRI of Patients With Aortic Disease.
|
N/A | |
Not yet recruiting |
NCT02221921 -
Safety and Efficacy Study of MicroPort's Transcatheter Aortic Valve and Delivery System for TAVI
|
N/A | |
Terminated |
NCT02128841 -
Comparison of Antithrombotic Treatments After Aortic Valve Replacement. Rivaroxaban: A New Antithrombotic Treatment for Patients With Mechanical Prosthetic Aortic Heart Valve.
|
Phase 2 | |
Active, not recruiting |
NCT01194362 -
A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease
|
||
Not yet recruiting |
NCT05975567 -
Deploying Novel Imaging Modalities Towards a Three-dimensional (3D) CARDIOvascular PATHology
|
||
Recruiting |
NCT06025149 -
The Study on the Use of "UniLine" Bioprosthesis in the Treatment of Isolated Aortic and Mitral Valve Diseases
|
||
Completed |
NCT05082337 -
The SAVVY Guidewire in Transcatheter Aortic Valve Replacement Procedures
|
N/A | |
Completed |
NCT05193760 -
Robustness Check of Placement and Measurement Algorithms for Blood Flow Measurement on Common Carotid Artery
|
||
Not yet recruiting |
NCT05941455 -
A Prospective Multicenter Pivotal Study to Evaluate Safety and Effectiveness of Venus-Neo Surgical Aortic Valve
|
N/A | |
Active, not recruiting |
NCT04950192 -
Philips Intracardiac Echocardiography (ICE) Clinical Registry
|
||
Active, not recruiting |
NCT03924661 -
SJM Masters HP 15mm Rotatable Mechanical Heart Valve as Aortic Valve Replacement Therapy
|
||
Completed |
NCT04073875 -
18F-GP1 PET-CT to Detect Bioprosthetic Aortic Valve Thrombosis
|
||
Recruiting |
NCT03121053 -
Preventing contrAst Induced Nephropathy After TranscathEter Aortic Valve Replacement
|
Phase 4 | |
Completed |
NCT02000544 -
Clinical Evaluation of a Modular Extracorporeal Circulation Circuit
|
N/A | |
Completed |
NCT02981004 -
PAR I - Patient-to-Annulus Relation I
|
||
Completed |
NCT02688153 -
EDWARDS INTUITY Valve System CADENCE Study
|
N/A | |
Recruiting |
NCT06126367 -
Assessment of Lipoprotein(a) and Endogenous Fibrinolysis in Atherosclerotic Cardiovascular Disease/Aortic Valve Disease
|