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Vitamin K Supplement for Inhibition of the Progress in Aortic Valve Calcification — 08-002  

Aortic Valve Calcification Clinical Trial

Official title:
Vitamin K Containing Nutritional Supplement for Activation of Matrix-GIa-proteins (MGP) and Inhibition of Aortic Valve Calcification Process

Clinical Trial Summary

In this mono-center,open,three-armes, controlled, randomized phase I study the progress of aortic valve calcification with and without vitamin K supplementation will be investgated. This will be done by means of measurements of concentrations from osteocalcine and MPG in blood serum, echocardiography, cardiac computed tomography and cardiac MRI

Clinical Trial Description

Patients will be allocated to two groups with either

1. additional intake of 2 mg vitamin k1 daily

2. controll group without additional intake of Vitamin K

Treatment group a will include 100 patients, the controll group should include 100 patients. None of all patients should require renal dialysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00785109
Study type Interventional
Source RWTH Aachen University
Contact
Status Completed
Phase Phase 3
Start date January 2010
Completion date August 2015
View Details
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