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Anxiety, Separation clinical trials

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NCT ID: NCT01470469 Completed - Anxiety, Separation Clinical Trials

SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)

Start date: January 4, 2012
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety and tolerability of SPD503 in subjects aged 6-17 years with GAD, SAD, or SoP based on treatment emergent adverse events (TEAEs), vital signs and ECGs.

NCT ID: NCT01416805 Completed - Clinical trials for Generalized Anxiety Disorder

Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers

Start date: August 2011
Phase: Phase 3
Study type: Interventional

This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety disorders in community health centers. The first phase of the study will offer insight into the feasibility of providing this intervention in community health centers, while the second phase will compare CCBT to treatment as usual.

NCT ID: NCT01178385 Completed - Autism Clinical Trials

Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

Start date: April 2010
Phase: Phase 2/Phase 3
Study type: Interventional

Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning. Co-occurring conditions, such as anxiety, are common and may cause substantial distress and impairment beyond that caused by the autism diagnosis. Although effective interventions have been developed for typically developing youth with anxiety disorders, this approach needs to be adapted for children with autism. Accordingly, we are proposing a randomized controlled trial to examine the effectiveness of CBT relative to treatment as usual (TAU) in 46 youth ages 7-11 with autism spectrum disorders and comorbid anxiety disorder(s).

NCT ID: NCT01160588 Completed - Clinical trials for Generalized Anxiety Disorder

Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents

Start date: July 2010
Phase: Phase 4
Study type: Observational

This study will attempt to identify gene and brain activity markers that predict whether children and adolescents with anxiety disorders will respond to selective serotonin reuptake inhibitor medications or Cognitive Behavioral Therapy (CBT).

NCT ID: NCT00787397 Completed - Clinical trials for Generalized Anxiety Disorder

Sleep, Mood, and Behavior Study

Start date: February 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether improving sleep in children and adolescents with anxiety disorder will further enhance affective, clinical, and social functioning.

NCT ID: NCT00774150 Completed - Clinical trials for Generalized Anxiety Disorder

Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment Study

CATS
Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate neurobehavioral, affective, and social processes that may influence and predict treatment response in pediatric anxiety disorders.

NCT ID: NCT00735995 Completed - Clinical trials for Generalized Anxiety Disorder

Effectiveness of Cognitive Behavioral Therapy (CBT) for Child Anxiety Disorders in Community Clinics in Norway

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the effectiveness of a cognitive-behavioral intervention for children aged 7 to 12 years with anxiety disorders who are referred to ordinary community clinics. The treatment will be conducted as individual therapy or group therapy.

NCT ID: NCT00593515 Completed - Clinical trials for Generalized Anxiety Disorder

Effects of Parental Behavior on Child Anxiety Regulation

Start date: March 2000
Phase: Phase 2
Study type: Interventional

Does parenting style affect emotion regulation among children who initially demonstrate high levels of fear and anxiety? Although recent correlational research has demonstrated a linkage between parental behaviors, such as excessive intrusiveness, and children's manifestations of fear and anxiety, it is not clear if parenting behaviors directly influence children's ability to regulate these emotions. Alternatively, these parental behaviors may be elicited by children who express fears and anxieties more frequently than other children do. Experimental research designs would offer a more definitive test of these competing explanations of the extant correlational findings. Intervention studies, in particular, can test whether experimentally manipulating current family interaction patterns affects children's ability to regulate emotion. This study provides a preliminary experimental test of the relationship between parental behavior and children's regulation of fear and anxiety. Some 40 clinically anxious youth, aged 6-13, were randomly assigned to a family intervention program for childhood anxiety problems, which includes extensive parent communication training, or a child intervention program without parent-training. By comparing these two interventions, we tested if it was possible to improve parenting behaviors—such as intrusiveness—through intensive parent-training, above and beyond the effects of involving children in a child intervention program. We then tested the impact of this change in parental behaviors on children's ability to regulate fear and anxiety. We hypothesized that parent-training would reduce intrusiveness, which would in turn improve children's anxiety outcomes.

NCT ID: NCT00586586 Completed - Clinical trials for Generalized Anxiety Disorder

Effectiveness Study of CBT for Anxiety in Children

ATACA
Start date: January 2, 2008
Phase: Phase 2
Study type: Interventional

The study aims to evaluate the effectiveness of a cognitive behaviour therapy program (FRIENDS) for anxiety disorders in children aged 8-15 years who have been referred to child and adolescent mental health clinics in Western Norway.

NCT ID: NCT00569829 Completed - Clinical trials for Generalized Anxiety Disorder

Modular Cognitive Behavioral Therapy for the Treatment of Child Anxiety Disorders in Elementary School Settings

KATES
Start date: January 2004
Phase: Phase 2
Study type: Interventional

Although cognitive behavioral therapy (CBT) has been found to be efficacious in the treatment of child anxiety disorders, little progress has been made in the dissemination of such treatments to real-world practice settings. Clinical trials conducted in practice settings can demonstrate the degree to which evidence-based treatments are appropriate for larger scale dissemination. This study evaluates CBT as a treatment for child anxiety disorders in the elementary school clinic setting. A randomized, controlled trial design has been employed, comparing immediate treatment and a three-month waitlist. The trial is being conducted in several Los Angeles area elementary schools and is only available to children in these particular schools. To ensure that the CBT intervention is flexible and capable of matching the characteristics of various school settings, clinicians, and referred children, a modular treatment approach is employed. The study design includes elements to ensure high quality data, such as the use of independent evaluators and tests of treatment fidelity. Children, ages 5 to 12 years, are referred by teachers and staff or are identified as having high anxiety in concurrent studies. All participating children have DSM-IV diagnoses of separation anxiety disorder, generalized anxiety disorder, or social phobia, according to a semi-structured diagnostic interview. Therapy and clinical supervision is provided by the research team. It is hypothesized that children receiving immediate treatment will have significantly lower anxiety scores than children assigned to the waitlist at the posttreatment/postwaitlist assessment. If results are favorable, further exploration of dissemination of CBT into school clinic settings may be indicated.