Sequencing CBT for Child Anxiety: CBT Plus Sertraline Versus Switch to Sertraline

Anxiety Disorder of Adolescence Clinical Trial

Official title: Sequencing CBT for Child Anxiety: CBT Plus Sertraline Versus Switch to Sertraline

Status Terminated

Clinical Trial Summary

The purpose of this study is to determine whether cognitive behavioral therapy (CBT) in combination with sertraline (SRT) is more effective than SRT alone in treating children and adolescents with anxiety disorders (after an initial 8 weeks of CBT).

Clinical Trial Description

This project proposes to conduct a pilot study to collect preliminary data on a 'personalized adaptive treatment' approach for children and adolescents with anxiety disorders. All youth patients in this two site study will first receive CBT and all then will be re-assessed at mid-treatment (8 sessions). Patients who show a partial response or no response following 8 sessions of CBT will be randomized to either a switch to SRT alone or CBT augmentation with SRT. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Anxiety Disorder of Adolescence
• Anxiety Disorders

• NCT number: NCT01977729
• Study type: Interventional
• Source: Yale University
• Status: Terminated
• Phase: Phase 2
• Start date: October 2013
• Completion date: September 2014