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Antisocial Personality Disorder clinical trials

View clinical trials related to Antisocial Personality Disorder.

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NCT ID: NCT06028620 Completed - Clinical trials for Psychopathic Personality Trait

Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children. The main question it aims to answer are: which are the clinical characteristics of maltreated children before and after a psychological intervention? what changes in brain emotional processing after a psychological intervention? and what is the effect of serotonin transporter variants after a psychological therapy? Participants were assessed before and after intervention with: - clinical measures of anxiety, depression post-traumatic stress and callous-unemotional traits - functional neuroimaging techniques to measure brain activity. - A sample of buccal epithelial cells to obtain information on serotonin transporter. Researchers will compare maltreated children with a group on non-maltreated children to see if there are differences on psychological characteristics and on brain activity before treatment.

NCT ID: NCT06018298 Completed - Mental Disorder Clinical Trials

Evaluation of Excellence in Italy's Residence for Execution of Security Measure

ITAL-EE-REMS
Start date: July 1, 2018
Phase:
Study type: Observational

The model of care for forensic psychiatry in Italy was changed by law (Law 81/2014) so that the six legacy secure forensic hospitals (Judicial Psychiatric Hospitals, OPG) were closed and new secure community residences for the execution of security measures (REMS) were opened in each of the 20 regions of Italy. This transition was in place by 2015. This observational study evaluates the health gains for patients both previously in OPGs and those admitted first to REMS. Health gains assessed include recovery measured by symptoms, function, need for therapeutic security and recovery of legal autonomy.

NCT ID: NCT05383300 Completed - Clinical trials for Antisocial Personality Disorder

Intranasal Oxytocin in Antiosocial Personality Disorder and Psychopathy

OXYASP
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

A pharmacoimaging study of oxytcoin in antisocial personality disorder and psychopathy

NCT ID: NCT04903938 Completed - Clinical trials for Antisocial Personality Disorder

Positive Psychotheraphy and Antisocial Personality Disorder: Crime, Aggression, Anger

Start date: January 2013
Phase:
Study type: Observational

Studies on Antisocial Personality Disorder (ASPD), in which criminal behaviors, aggression and anger behaviors are frequently seen, are very rare. Developed by Nosrat Peseschkian, positive psychotherapy is an eclectic therapy approach born from the psychodynamic approach, existential-humanist approach, behavioral approach and intercultural therapy approach. Psychodynamic psychotherapy is a humanistic, psychodynamic, resource-focused, conflict-solving, integrative and intercultural approach that has its own unique intervention methods as well as the features of other therapy theories. In this study, it was aimed to determine the primary and secondary abilities of individuals with criminal and non-criminal antisocial personality disorder within the scope of positive psychotherapy, to compare these abilities with respect to healthy individuals, and to examine the effects on crime, aggression behavior and anger levels.

NCT ID: NCT04865562 Completed - Dyssocial Behavior Clinical Trials

Hormones and Decision Making

Start date: March 1, 2015
Phase: Phase 4
Study type: Interventional

An investigation of the neuropsychological processes underlying ethical decision making.

NCT ID: NCT04746027 Completed - Autism Clinical Trials

Empathy, Psychopathy and Autism: Behavioural Associations and the Role of an Oxytocin Receptor Polymorphism in a Non-clinical Adult Population

Start date: July 1, 2017
Phase:
Study type: Observational

This is an investigation into the associations between psychopathic traits, autistic traits and empathy (cognitive and affective) in the general population as measured using three self report questionnaires and one behavioural task. Participants will also be genotyped for OXTR rs53576 to assess whether this mutation associates with any of the behavioural traits investigated.

NCT ID: NCT03971682 Completed - Conduct Disorder Clinical Trials

The Efficacy of a Compassion Focused Therapy-based Intervention in Detained Youth

PSYCOMP
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

This non-randomized controlled trial with a control group aimed to assess the efficacy of a 20-session individualized Compassion Focused Therapy-based intervention, the PSYCHOPATHY.COMP, in reducing psychopathic traits (primary outcomes), aggression, shame, emotion regulation problems, and fears of compassion, as well as in increasing social safeness, self-compassion, and compassion towards others (secondary outcomes). The PSYCHOPATHY.COMP's impact on psychophysiological (i.e., Heart Rate/Heart Rate Variability) and behavioral indicators (i.e., number disciplinary infractions and number of days in punishment) were also tested, in order to ascertain if changes observed in self-report questionnaires were reflected in more adjusted psychophysiological and behavioral patterns. Mental Health disorders, as well as the number of Conduct Disorder criteria, were also tested as moderators of treatment effects.

NCT ID: NCT03834467 Completed - Clinical trials for Psychopathic Personality Trait

Testing a Shortened Version of the AlAn's Game

Start date: May 8, 2019
Phase: N/A
Study type: Interventional

It has been demonstrated that behavior on the AlAn's (altruism-antisocial) game is related to Moral Elevation response. Moral Elevation is a positive response to another's act of generosity "of charity, gratitude, fidelity, generosity or any other strong display of virtue". The constellation of emotional, physical and psychological aspects of a Moral Elevation response have been well described. Moral Elevation can be elicited with stimulus stories or videos and measured with self-report questionnaires. The experience of Moral Elevation is associated with subsequent prosocial and affiliative behaviors. Additionally, the research has linked Moral Elevation response with behavior on the AlAn's game. This study will test whether behavior on the AlAn's Short Game v.2 is related to Moral Elevation response and extend prior work by testing whether viewing the Moral Elevation stimulus prior to playing the AlAn's Short Game v.2 is associated with differences in game behavior. The study will also test whether psychopathic traits will correlate with game behavior.

NCT ID: NCT03627312 Completed - Antisocial Behavior Clinical Trials

Omega-3 Supplements to Reduce Antisocial Behaviour in Young Offenders

Start date: March 1, 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The study aims to examine the effects of providing omega-3 supplements on young offenders' antisocial behaviour. Participants will be randomized into three groups: (1) Omega-3, (2) Placebo and (3) Treatment as Usual. Self report and correctional officer ratings of behaviour will be assessed at 0 months (baseline), 3 months (end of supplementation), 6 months and 12 months. The investigators hypothesize that omega-3 supplementation will reduce antisocial behaviour among the young offenders.

NCT ID: NCT03036683 Completed - Aggression Clinical Trials

Transcranial Direct Current Stimulation in Offenders

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

This study investigates the effect of upregulating prefrontal cortex activity on risk-taking, and antisocial and aggressive behavior in violent offenders. In the double-blind, randomized controlled trial, using a within-subject crossover design, each participant will undergo anodal transcranial direct current stimulation of the right dorsolateral prefrontal cortex and sham stimulation. After each stimulation session, neural activity and behavioral responses to tasks assessing risk-taking and aggressive behavior will be recorded. The effect of tDCS on violent offenders will also be assessed in comparison to age and gender-matched healthy controls.